ID K4JCM6_9HYPO Unreviewed; 535 AA.
AC K4JCM6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 08-NOV-2023, entry version 29.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
GN Name=RPB1 {ECO:0000313|EMBL:AFU81887.1};
OS Fusarium tricinctum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium tricinctum species complex.
OX NCBI_TaxID=61284 {ECO:0000313|EMBL:AFU81887.1};
RN [1] {ECO:0000313|EMBL:AFU81887.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 25481 {ECO:0000313|EMBL:AFU81887.1};
RX PubMed=23357352; DOI=10.1016/j.fgb.2012.12.004;
RA O'Donnell K., Rooney A.P., Proctor R.H., Brown D.W., McCormick S.P.,
RA Ward T.J., Frandsen R.J., Lysoe E., Rehner S.A., Aoki T., Robert V.A.,
RA Crous P.W., Groenewald J.Z., Kang S., Geiser D.M.;
RT "Phylogenetic analyses of RPB1 and RPB2 support a middle Cretaceous origin
RT for a clade comprising all agriculturally and medically important
RT fusaria.";
RL Fungal Genet. Biol. 52:20-31(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
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DR EMBL; JX171516; AFU81887.1; -; Genomic_DNA.
DR AlphaFoldDB; K4JCM6; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..130
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04983"
FT DOMAIN 159..261
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF05000"
FT DOMAIN 268..535
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04998"
FT DOMAIN 334..518
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04992"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFU81887.1"
FT NON_TER 535
FT /evidence="ECO:0000313|EMBL:AFU81887.1"
SQ SEQUENCE 535 AA; 59672 MW; 36238FA09F16DAF8 CRC64;
FLTKEQIMNC MLWVPNWDGV IPQPAIYKPR PRWTGKQLIS MVIPKEVSLF NGTDDNENAP
LRDEGLLIQS GQLMYGLLTK KSVGAAAGGI VHISYNELGP EGAMAFLNGV QQVVTYWLLN
NGHSIGIGDT IPDAATIAKV QVHIDEEKAE VARLTAMATA NELEALPGMN VRATFENKVS
MALNQARDKA GTTTQKSLKD SNNAVTMASS GSKGSSINIS QMTALVGQQI VEGKRIPFGF
KYRTLPHFTK DDYSPEARGF VENSYLRGLT PSEFFFHAMA GREGLIDTAV KTAETGYIQR
RLVKALEDLS ARYDGTVRNS LGDIVQFLYG EDGLDAMIIE KQKLGILNMS NSAFEKKYRL
DLANPPDWFR HDYEFGNELT GDRASMSLLD EEWEALRYDR KRIRLINQSK GNEEMMQLPL
NITRIIESAK RVFNVKANDR SNLRPSDVIP GVRNMLENMK IVRGTDEISL EADANASILF
KALLRSRLAF KEVVKEHRLN KLAFDYILGE LQNRWDRAFV NPGEMVGVLA AQSIG
//
