ID K4L0E9_9FIRM Unreviewed; 271 AA.
AC K4L0E9;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Formate hydrogenlyase subunit 7 {ECO:0000313|EMBL:AFV04767.1};
GN ORFNames=DCF50_p760 {ECO:0000313|EMBL:AFV04767.1};
OS Dehalobacter sp. CF.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Dehalobacter.
OX NCBI_TaxID=1131462 {ECO:0000313|EMBL:AFV04767.1, ECO:0000313|Proteomes:UP000000482};
RN [1] {ECO:0000313|EMBL:AFV04767.1, ECO:0000313|Proteomes:UP000000482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF {ECO:0000313|EMBL:AFV04767.1};
RX PubMed=23284863; DOI=10.1371/journal.pone.0052038;
RA Tang S., Gong Y., Edwards E.A.;
RT "Semi-automatic in silico gap closure enabled de novo assembly of two
RT dehalobacter genomes from metagenomic data.";
RL PLoS ONE 7:E52038-E52038(2012).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the FrhG family.
CC {ECO:0000256|ARBA:ARBA00010870}.
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DR EMBL; CP003870; AFV04767.1; -; Genomic_DNA.
DR RefSeq; WP_015042770.1; NC_018867.1.
DR AlphaFoldDB; K4L0E9; -.
DR STRING; 1131462.DCF50_p760; -.
DR KEGG; dec:DCF50_p760; -.
DR PATRIC; fig|1131462.4.peg.770; -.
DR eggNOG; COG1143; Bacteria.
DR eggNOG; COG3260; Bacteria.
DR HOGENOM; CLU_055737_5_1_9; -.
DR Proteomes; UP000000482; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.30.70.3270; -; 1.
DR Gene3D; 3.40.50.12280; -; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR006137; NADH_UbQ_OxRdtase-like_20kDa.
DR InterPro; IPR006138; NADH_UQ_OxRdtase_20Kd_su.
DR PANTHER; PTHR42989:SF1; FORMATE HYDROGENLYASE SUBUNIT 7-RELATED; 1.
DR PANTHER; PTHR42989; HYDROGENASE-4 COMPONENT I; 1.
DR Pfam; PF13237; Fer4_10; 1.
DR Pfam; PF01058; Oxidored_q6; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF56770; HydA/Nqo6-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS01150; COMPLEX1_20K; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000313|EMBL:AFV04767.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000482}.
FT DOMAIN 30..59
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 61..90
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 271 AA; 29573 MW; 80244E1AD82A1949 CRC64;
MFKTLKKIIQ YPRLTQEYPK IPASGGQFLG QTEINPEKCS FCGECVLRCP SQAIVMAKEA
GIIGINYDAC IFCVLCEEVC PTGAVTTTNQ FELAEKDKAM LHVDKTVAVK NQTLIIDENN
LPDTSYKAVC RDLEAKIKKM FGRSLQIREV DSGSCNGCDY EINALNNPVN DIERLGISFV
ASPRHADMLL VTGTATRNMQ QALVKTYHAA PDPKLVVAVG ACACSGGIFK DSYATNNGID
TIVPVDVYIP GCPPRPQAII YGILKALDRM K
//
