ID K4L5S2_9FIRM Unreviewed; 307 AA.
AC K4L5S2;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Cell division inhibitor {ECO:0000313|EMBL:AFV05961.1};
GN ORFNames=DCF50_p1959 {ECO:0000313|EMBL:AFV05961.1};
OS Dehalobacter sp. CF.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Dehalobacter.
OX NCBI_TaxID=1131462 {ECO:0000313|EMBL:AFV05961.1, ECO:0000313|Proteomes:UP000000482};
RN [1] {ECO:0000313|EMBL:AFV05961.1, ECO:0000313|Proteomes:UP000000482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF {ECO:0000313|EMBL:AFV05961.1};
RX PubMed=23284863; DOI=10.1371/journal.pone.0052038;
RA Tang S., Gong Y., Edwards E.A.;
RT "Semi-automatic in silico gap closure enabled de novo assembly of two
RT dehalobacter genomes from metagenomic data.";
RL PLoS ONE 7:E52038-E52038(2012).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. SDR39U1 subfamily. {ECO:0000256|ARBA:ARBA00009353}.
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DR EMBL; CP003870; AFV05961.1; -; Genomic_DNA.
DR RefSeq; WP_015044002.1; NC_018867.1.
DR AlphaFoldDB; K4L5S2; -.
DR STRING; 1131462.DCF50_p1959; -.
DR KEGG; dec:DCF50_p1959; -.
DR PATRIC; fig|1131462.4.peg.1975; -.
DR eggNOG; COG1090; Bacteria.
DR HOGENOM; CLU_047373_0_3_9; -.
DR Proteomes; UP000000482; Chromosome.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd05242; SDR_a8; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013549; DUF1731.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR010099; SDR39U1.
DR NCBIfam; TIGR01777; yfcH; 1.
DR PANTHER; PTHR11092:SF0; EPIMERASE FAMILY PROTEIN SDR39U1; 1.
DR PANTHER; PTHR11092; SUGAR NUCLEOTIDE EPIMERASE RELATED; 1.
DR Pfam; PF08338; DUF1731; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:AFV05961.1};
KW Cell division {ECO:0000313|EMBL:AFV05961.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000482}.
FT DOMAIN 3..219
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
FT DOMAIN 254..299
FT /note="DUF1731"
FT /evidence="ECO:0000259|Pfam:PF08338"
SQ SEQUENCE 307 AA; 34181 MW; 4FFB5614EDFA33FF CRC64;
MNVLIFGGTG FLGRNLTKEL ISNGYQVAVI TRNQKITANK VEGDVKLIEW DNSSSLSSAY
DFKEFDVVIN FAGESIGNHR WTESVKQEIL NSRINTTRFI VNAINDGIIN PKVLISASAV
GYYGSRQDDK ITENEGPGQD FLAGVCRKWE AEAYKVQNEL TRVVTIRTGI VLGSQGALTA
MVIPFKFYVG GPLGKGNQWL PWIHIQDLIR MIRYIIEHDE VTGPVNGTAP EPVRMEGFTK
ILGEVLKRPS WFPVPEFLLK IALGQMSEML LHGQRAIPQK ISDVGFEFKF PNLRSALVDA
LGNRNVV
//
