ID K4LWI6_THEPS Unreviewed; 672 AA.
AC K4LWI6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Sigma54 specific transcriptional regulator {ECO:0000313|EMBL:AFV12354.1};
GN OrderedLocusNames=Tph_c21610 {ECO:0000313|EMBL:AFV12354.1};
OS Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 26808 / PB).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermacetogenium.
OX NCBI_TaxID=1089553 {ECO:0000313|EMBL:AFV12354.1, ECO:0000313|Proteomes:UP000000467};
RN [1] {ECO:0000313|EMBL:AFV12354.1, ECO:0000313|Proteomes:UP000000467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-254 / DSM 26808 / PB
RC {ECO:0000313|Proteomes:UP000000467};
RX PubMed=23259483; DOI=10.1186/1471-2164-13-723;
RA Oehler D., Poehlein A., Leimbach A., Muller N., Daniel R., Gottschalk G.,
RA Schink B.;
RT "Genome-guided analysis of physiological and morphological traits of the
RT fermentative acetate oxidizer Thermacetogenium phaeum.";
RL BMC Genomics 13:723-723(2012).
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DR EMBL; CP003732; AFV12354.1; -; Genomic_DNA.
DR RefSeq; WP_015051229.1; NZ_KI912609.1.
DR AlphaFoldDB; K4LWI6; -.
DR STRING; 1089553.Tph_c21610; -.
DR KEGG; tpz:Tph_c21610; -.
DR eggNOG; COG3284; Bacteria.
DR HOGENOM; CLU_000445_8_12_9; -.
DR OrthoDB; 9803970at2; -.
DR Proteomes; UP000000467; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR32071:SF119; SIGMA-54 INTERACTING PROTEIN; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000467};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 218..272
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 347..577
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 672 AA; 74568 MW; AF813C9DDF3DBECA CRC64;
MPNNGTVSRS IAIAWKIFVN TGKIPATVRS EIAESWLRSR RAGVDPWDGV SHRVLSAEQL
EALLYKKRSL IDVARPFMTN LYHFVAGSGF IVLLSDEQGF IMEVMGDSDI LKNAAELNLI
RGASWIEEET GTNGLGTALA IRRPIQVSGE EHYCQKVHGW TCSAAPIYDD DGRVIGALQM
SGPSFKTHPH TLGMVVAAVE AIRSQLRLQR RNSELVLLNN RLGNIFHTVS DGVVVVDRNG
LIEQVNPAAE KILSKPDSEI RGAMFKEFVE RDPGIEELLT TGKSYTDKEV IVNNRTGIVY
CLSSGKPIQD EKGAITDGVI FLNPINKIRN LVNRLSGAQA TYTFADIIGR NKKLLKAVQL
AKLAATNDSN VLLQGESGTG KEVFAQAIHN ASSRRNGPFI AVNCGAIPRE LIGSELFGYD
EGAFTGARRG GRPGKFELAS GGTLFLDEIG DMPLEHQVAL LRVLQDKRIT RIGGEKVIAV
DVRVICATNK DLKLEVARGN FREDLFYRLN VISISLPPLR ERREDIPLLF DVFFEEICKK
MHVDIRDVDP RVIPCLQRYH WPGNIREFQN VIERMVNVAA GQSIRLEHLP EEIVCPHSSG
LQPEGDGAPR ETTLLAERNR IKRLLAEKER QEISLLLVKN KGNLSKVARE LGISRSSLYR
KLRKLDILSK GD
//
