ID K4PUP6_9GAMM Unreviewed; 179 AA.
AC K4PUP6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Methionyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030904};
DE Flags: Fragment;
GN Name=metG {ECO:0000313|EMBL:AFV66700.2};
OS Aeromonas sp. REm-amp_240.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Aeromonas.
OX NCBI_TaxID=1246262 {ECO:0000313|EMBL:AFV66700.2};
RN [1] {ECO:0000313|EMBL:AFV66700.2}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=REm-amp_240 {ECO:0000313|EMBL:AFV66700.2};
RX PubMed=23204414; DOI=10.1128/AEM.03171-12;
RA Voolaid V., Tenson T., Kisand V.;
RT "Aeromonas and Pseudomonas Species Carriers of ampC FOX Genes in Aquatic
RT Environments.";
RL Appl. Environ. Microbiol. 79:1055-1057(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-
CC methionyl-tRNA(Met); Xref=Rhea:RHEA:13481, Rhea:RHEA-COMP:9667,
CC Rhea:RHEA-COMP:9698, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:57844, ChEBI:CHEBI:78442, ChEBI:CHEBI:78530,
CC ChEBI:CHEBI:456215; EC=6.1.1.10;
CC Evidence={ECO:0000256|ARBA:ARBA00001234};
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DR EMBL; JX899536; AFV66700.2; -; Genomic_DNA.
DR AlphaFoldDB; K4PUP6; -.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004825; F:methionine-tRNA ligase activity; IEA:InterPro.
DR GO; GO:0006418; P:tRNA aminoacylation for protein translation; IEA:InterPro.
DR Gene3D; 2.170.220.10; -; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR023458; Met-tRNA_ligase_1.
DR InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR InterPro; IPR029038; MetRS_Zn.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR45765; METHIONINE--TRNA LIGASE; 1.
DR PANTHER; PTHR45765:SF1; METHIONINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR Pfam; PF09334; tRNA-synt_1g; 1.
DR SUPFAM; SSF57770; Methionyl-tRNA synthetase (MetRS), Zn-domain; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000313|EMBL:AFV66700.2}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 1..179
FT /note="Methionyl/Leucyl tRNA synthetase"
FT /evidence="ECO:0000259|Pfam:PF09334"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFV66700.2"
FT NON_TER 179
FT /evidence="ECO:0000313|EMBL:AFV66700.2"
SQ SEQUENCE 179 AA; 20109 MW; 9A396E15DABB4E61 CRC64;
GSIHLGHMLE HIQADIWVRY QRMRGHQVHF ICADDAHGTP IMLKAQQMGI TPEEMIAAVS
KEHQTDFAGF NISFDNYHST HSDENRELAE LIYGRLKAGG FIKGRTITQL FDPEKSMFLP
DRFVKGTCPK CKSPEQYGDN CDSCGATYSP TELIDPKSAV SGATPVMKDS EHFFFDLPQ
//
