ID K5DGR6_9BACE Unreviewed; 939 AA.
AC K5DGR6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=HMPREF1057_00978 {ECO:0000313|EMBL:EKJ92143.1};
OS Bacteroides finegoldii CL09T03C10.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=997888 {ECO:0000313|EMBL:EKJ92143.1, ECO:0000313|Proteomes:UP000007995};
RN [1] {ECO:0000313|EMBL:EKJ92143.1, ECO:0000313|Proteomes:UP000007995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL09T03C10 {ECO:0000313|EMBL:EKJ92143.1,
RC ECO:0000313|Proteomes:UP000007995};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides finegoldii CL09T03C10.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKJ92143.1}.
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DR EMBL; AGXW01000002; EKJ92143.1; -; Genomic_DNA.
DR RefSeq; WP_007760148.1; NZ_JH951901.1.
DR AlphaFoldDB; K5DGR6; -.
DR HOGENOM; CLU_002926_1_1_10; -.
DR OrthoDB; 9766741at2; -.
DR Proteomes; UP000007995; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307:SF11; ALPHA-L-RHAMNOSIDASE; 1.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000007995};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..939
FT /note="alpha-L-rhamnosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003882814"
FT DOMAIN 200..370
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 395..488
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 507..855
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 858..930
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 939 AA; 106476 MW; 26DBF61018BA71A0 CRC64;
MNIKKYLLLF LCLPCFMQAK TITISRLTCE MQDGLVVVEG SPRLGWVMES PENGTRQSAY
EIDIREAFTG RSVWNSGKVY STQSQLVSIE GADIRPDNPF NYSWRVRVWD ETDAPSEWSR
EAKFRSASSR LSEGKWIGAI TRQNAHLPEG RKFHGGELKK PEVKAAWEAV DTLAKKSICL
RRTFQVGDRT EGNTNRQSGK KIVEATAYVC GLGFYEFSLN GKKVGNSEFA PLWSDYDKTV
FYNTYDVTEQ LRHGENAVGI LLGNGFYNVQ GGRYRKLQIS FGPPTLLFEL VINYEDGTST
TLRSDNDWKY DFSPITFNCI YGGEDYDARR EQKGWNQVGF DDSHWRPVVI QEAPKGILRP
QMAPPVKIME RYDIQKVTKL NAEQVASASK STKRTVDPSA FVLDMGQNLA GFPEITVCGK
RGQKVTLLVA EALTDEGACN QRQTGRQHYY EYTLKGEGDE TWHPRFSYYG FRYIQVEGAV
LKGQKNPQKL PVLKNIQSCF VFNSAKKVST FESSNRIFNA AHRLIEKAVR SNMQSVFTDC
PHREKLGWLE QVHLNGPGLL YNYDLTAYAP QIMQNMADAQ HANGAMPTTA PEYVIFEGPG
MDAFAESPEW GGSLVIFPFM YYETYGDDSL IKKYYPNMRR YVDYLKTRAD KGILSFGLGD
WYDYGDFRAG FSRNTPVPLV ATAHYYMTVM YLIKAAKMVG NDFDIHYYTS LAHEILAAFN
KCFLHKETAQ YGTGSQCSNA LPLFLQMTQD ADEQGNYQPD AKLNEKVLMN LIKDVEAHGN
RLTTGDVGNR YLIQTLARNG QHELIYKMFN HEEAPGYGFQ LKFGATTLTE QWDPRQGSSW
NHFMMGQIDE WFFNSLVGIR PSTTYQKFII APQPVGDLKY VKASYETLYG TIVVDWTSQN
GTFTLNISVP VNTTAVVYLP GEKEPKEIQS GTYQLVCAK
//
