ID K5E263_RHOBT Unreviewed; 1002 AA.
AC K5E263;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=RBSH_04939 {ECO:0000313|EMBL:EKJ99855.1};
OS Rhodopirellula baltica SH28.
OC Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC Rhodopirellula.
OX NCBI_TaxID=993517 {ECO:0000313|EMBL:EKJ99855.1, ECO:0000313|Proteomes:UP000007993};
RN [1] {ECO:0000313|EMBL:EKJ99855.1, ECO:0000313|Proteomes:UP000007993}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH28 {ECO:0000313|EMBL:EKJ99855.1,
RC ECO:0000313|Proteomes:UP000007993};
RX PubMed=23273849;
RA Wegner C.E., Richter-Heitmann T., Klindworth A., Klockow C., Richter M.,
RA Achstetter T., Glockner F.O., Harder J.;
RT "Expression of sulfatases in Rhodopirellula baltica and the diversity of
RT sulfatases in the genus Rhodopirellula.";
RL Mar. Genomics 0:0-0(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKJ99855.1}.
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DR EMBL; AMCW01000137; EKJ99855.1; -; Genomic_DNA.
DR RefSeq; WP_007334374.1; NZ_AMCW01000137.1.
DR AlphaFoldDB; K5E263; -.
DR PATRIC; fig|993517.3.peg.5357; -.
DR Proteomes; UP000007993; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EKJ99855.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 56..225
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 252..411
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 815..895
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 11..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 758..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 895..935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1002 AA; 110925 MW; 6BB7E69FA3FA9A19 CRC64;
MAMRRWDAIH SCPPNTHRTK DRMSSLASNS NPSIDPESLL PRFGLKEFRP GQRDVVDALA
AGTDCLCVMP TGGGKSLCYQ LPSLAREGTT IVVSPLIALV KDQVDTLQRR GIQARLLNST
QSPGQQESVM EEMAAGKLDL IYVAPERLRN GRFLDVVPKA NVSLLAVDEA HCVSEWGHDF
RPDYSRLGRF RDRYLGGVQT IGLTATATPT VRDDICELLN LKQPRVFVTG FARTNLRFTV
TPCNNDVAKQ NALRDYLSKQ PGAGIIYGAT RKRCEEIAEW LPEKTGRKVG VYHAGMHPDE
RRRVQEAFMK GDLSAIVATN AFGMGIDKSD IRFVVHYNMP GSLEAYYQEA GRAGRDGEMS
QCLLLFAYSD RQIQEFFIEN RYPSRETVKK VYEYLLSREE DPIELTLDQV REAIGVRDGS
EAIGTSETLL SKAGALRRLD ASANQAVLRI DSDVPTLLDF LPREAKLKRQ VMTAIEKIVG
PRRGEDVFVR LSYLATRADV ERVQLTRTLR ELTKLKSFDY IPPFRGRAVH IMRRDVPFNQ
LKIDFEELAR RKQAEYEKLD SVIQFARSTS CRQHVILNYF GDPNAENCGR CDHCDPAGDC
MPKVDPSKLG SNLTTAKTLG ESGSVGALSE QAGIDMTALT TAIRVILSGV TRTHGRLGKN
LIAQMLAGSK NKKVTQLRLS RLSTYGMLTG LKQGELTDAM DSLLTVGLLD QKELNERRPT
VHMTDLGRQV MNGQVPLPPS LQLKFPLAKK LAKVASKIES GDVAEEEPGD IEPTVSAVMD
VPPKQPERPS PQQESSKTEA SVVAAEPLTS DDAEQLLDQD LSDRIKRFRR KRSAALNVAP
HRILSESTIK RVIESKPANA TQLEAVSGIS SEFIEAYGSD LLELIANTLA EHEIDCPPKS
ATPPSNHSVE PSEPAESPAV DPQPSPAADR PAEKVVDPSA WRNEYWTWKL CRDGYTLQQI
SEIRGESTEA LVDHLIAAAR AGQTIDPAWA DTPANAKRLR NL
//
