ID K5X088_AGABU Unreviewed; 1107 AA.
AC K5X088;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Cation-transporting P-type ATPase N-terminal domain-containing protein {ECO:0000259|SMART:SM00831};
GN ORFNames=AGABI1DRAFT_72076 {ECO:0000313|EMBL:EKM81196.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM81196.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH971388; EKM81196.1; -; Genomic_DNA.
DR RefSeq; XP_007328195.1; XM_007328133.1.
DR AlphaFoldDB; K5X088; -.
DR STRING; 597362.K5X088; -.
DR GeneID; 18831003; -.
DR KEGG; abp:AGABI1DRAFT72076; -.
DR eggNOG; KOG0202; Eukaryota.
DR HOGENOM; CLU_002360_3_1_1; -.
DR InParanoid; K5X088; -.
DR OMA; KMHACET; -.
DR OrthoDB; 203629at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0030001; P:metal ion transport; IEA:UniProt.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR42861; CALCIUM-TRANSPORTING ATPASE; 1.
DR PANTHER; PTHR42861:SF29; SECRETORY PATHWAY CALCIUM ATPASE, ISOFORM G; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00121; NAKATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 215..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..470
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 970..992
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1033..1053
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 161..236
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..49
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1107 AA; 119699 MW; 957D59A1BC7013C1 CRC64;
MGFERKKRNL TTIPITSPVG SSSGYYRQQG PTPNPHAMTN VRNPNRTPSP PASAYFPLLS
GDANAQLRPT PDADIHFAYS TTLRRHHSDG AALTSPGHFA AAVEAEATSL WKRALLTVTG
QPLPETPGLE NGLPTTRPAD PRPPPSAGTL QEEKKDTISA KFAHYSVADT VAWYRTNATT
GLLHSDIAHL QGQHGYNEFS VAAPEPLYLK FLKTIYESHL ILLLCGSATV SAIMGNVDDA
ISITVAVLIV LTVGFVQERR SEKSLEALNK LVPHHCHVIR QGETLHVLAN EIVPGDLVRF
STGDRIPADI RIVDAADLEI DESSFTGETT ARRKFSEPCA YIDGGSVDGI PGQSVALADR
SCIAYMGTLV RNGHGSGIVI ATGEETEFGV IFSMMQEVEE RRTPLQLSMD ELAKRLSILS
FGIIGIICLI GVLQQRSWLD MFTIGVSLAV AAIPEGLPIV TTVTLALGVL RMAKRKAIVK
KLHSVEALGS VSVVCSDKTG TLTKNEQTVT EAYAVDETIY LDPSSATQYT GTISPAMRKT
LEIGALCNNA LVERNEEGLF VGQSTDVALL NVLHLVGITD RRASFKRTSE KPFNSEQKYM
AVSGIHMDST FSSSSEHLRP PPNGTINANS REMYYIKGSI EIILDRCKFY YVNEESTPGL
DEETRKAIMT KAQSTASRGL RVIAMAYGYG NVDSFHNSSR SPSRASSPIH THGGEKDHLV
FVGFAAMVDP PRKGVADSVG LLQAGGVHVV MITGDAEHTA LAIAKDIGFR VGRQLHPLEG
AGQRYSGVLT GKAIDRLSKA QLKEIVGGIS VFARTTPKHK MRIVEAFQSR GAVVAMTGDG
VNDAPALKMA DIGLSMGKSG TDVAKEAADA ILVDDNFSTI LPAIEEGKSI FHNIQNFLSF
QLSTAAAALT LITLSTLLGL DNPLNAMQIL FVNILMDGPP SQSLGVDPVD PAVMRRPPRR
KNAPIITKRL LYRVIFSASL IVMGTLFIYT FALEDSDVSR REQTMTFTCF VFLDLVSAVQ
NRGLGCGLLQ NKMLVATVGI SALTQLALVY VPFLQAIFQT EALRGRDMGV IMGIAGSSFG
LHEVRRRWER RQEDKGGYES VAMEELA
//
