ID   K5XIU2_AGABU            Unreviewed;       952 AA.
AC   K5XIU2;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|Pfam:PF05729};
GN   ORFNames=AGABI1DRAFT_125705 {ECO:0000313|EMBL:EKM83242.1};
OS   Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS   10392) (White button mushroom).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX   NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM83242.1, ECO:0000313|Proteomes:UP000008493};
RN   [1] {ECO:0000313|Proteomes:UP000008493}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC   {ECO:0000313|Proteomes:UP000008493};
RX   PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA   Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA   Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA   Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA   Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA   Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA   Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA   Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA   Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT   "Genome sequence of the button mushroom Agaricus bisporus reveals
RT   mechanisms governing adaptation to a humic-rich ecological niche.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
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DR   EMBL; JH971386; EKM83242.1; -; Genomic_DNA.
DR   RefSeq; XP_007327028.1; XM_007326966.1.
DR   AlphaFoldDB; K5XIU2; -.
DR   GeneID; 18826355; -.
DR   KEGG; abp:AGABI1DRAFT125705; -.
DR   HOGENOM; CLU_317817_0_0_1; -.
DR   InParanoid; K5XIU2; -.
DR   OMA; ESHASWP; -.
DR   OrthoDB; 1487366at2759; -.
DR   Proteomes; UP000008493; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008493}.
FT   DOMAIN          375..544
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|Pfam:PF05729"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          223..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..145
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..166
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        223..248
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   952 AA;  107888 MW;  E46A3ADCD7E7C1A6 CRC64;
     MPSYPPEAFE TRSDPLHPQY GNVPKTNQRI LQGHCTVDGI LPQLKTQPAL GPHPPRTIQN
     AQNKSFQPIP HDFINESHAS WPLSEQDNQP SFLDPEIRRV RQSRQRGKLS LSDTVNLDNR
     RPQVITNNQM TAPQKAHSTI TPEMSLDRSF DMRPPPMREH FPPMSEDDIP DSGYGDLPSE
     HVIPGGPQDN NQVPHAPPPD VPATGRGSEN WLPSSFLRKR KWSNGASGSS QCLRNNQGES
     SSYFFSDKNN HVPRRHRQQS TIQHSRPPTG KFFIQRDSTS VAGAYSDPAN GFFSHSSNVV
     LQQPVMIDNS QRTYNQDDRP DGTLCWLENY IMQGAEFDSS DRVPPPRCHP GTRASIIERT
     INWVTDPQRE KSMRWIRGAA GVGKSAIVQT VFESLPENLR GGSVFFSRPN GRDNPDEVFP
     SIAYQLAVRD LSYRSYLAEL MLRDHRSLNK SMEDQFRLLF EEPFARQKLR DGQDTLVIAI
     DGLDECGGDP TYDDSGSARF RGRSPESAQR TIVELISSFV QQYPSFPFVW IIASRPERHL
     KATFYNQKIA PSFLEEDIPV DSTEACKDVE RYLNSEFTRI REDYDDLITM TPWPSSKEFS
     LITSKASGLF IFAEVVVRFI DGSNPIQQLK YALAAISKVS ASEVKETPLS VLDAMYIEIV
     SRVPHDLLES AKKIIGSIVL LGRDKVLKTS GTLPLICNIL GISRDVALTA LRHLHSVLLF
     PEGKKIESTR PRFYHASFRD FLEDESRSHE FSVKQYNMVD ELFKGLMRVS GRQRLDDHLL
     PWPRIGNAQA LVDMAKENKP FHFLHFHARI FSRTRPVSET LILPYLLNQD FAAKDCVNDL
     HGIVNMGVKQ LEIHDRLGVT SHMPIDSLGI TCDTVSQCNI SKSSFKTILR LYFASLNESN
     SSSEDIQSLR NVLCHWVATE PKRLVRVWGR ERFKRLVLIN FDLDGVVAFI GF
//