ID K5YZ20_9PROT Unreviewed; 948 AA.
AC K5YZ20;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Glutamate-ammonia-ligase adenylyltransferase {ECO:0000313|EMBL:EKN00204.1};
GN ORFNames=MXAZACID_06576 {ECO:0000313|EMBL:EKN00204.1};
OS Acidocella sp. MX-AZ02.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acidocella.
OX NCBI_TaxID=1214225 {ECO:0000313|EMBL:EKN00204.1, ECO:0000313|Proteomes:UP000006217};
RN [1] {ECO:0000313|EMBL:EKN00204.1, ECO:0000313|Proteomes:UP000006217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX-AZ02 {ECO:0000313|EMBL:EKN00204.1,
RC ECO:0000313|Proteomes:UP000006217};
RX PubMed=23405365;
RA Servin-Garciduenas L.E., Garrett R.A., Amils R., Martinez-Romero E.;
RT "Genome Sequence of the Acidophilic Bacterium Acidocella sp. Strain MX-
RT AZ02.";
RL Genome Announc. 1:E00041-12(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKN00204.1}.
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DR EMBL; AMPS01000081; EKN00204.1; -; Genomic_DNA.
DR RefSeq; WP_008493415.1; NZ_JH976207.1.
DR AlphaFoldDB; K5YZ20; -.
DR STRING; 1214225.MXAZACID_06576; -.
DR PATRIC; fig|1214225.3.peg.1274; -.
DR HOGENOM; CLU_006233_0_0_5; -.
DR Proteomes; UP000006217; Unassembled WGS sequence.
DR GO; GO:0008882; F:[glutamate-ammonia-ligase] adenylyltransferase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05401; NT_GlnE_GlnD_like; 2.
DR Gene3D; 1.20.120.1510; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 2.
DR Gene3D; 1.20.120.330; Nucleotidyltransferases domain 2; 2.
DR InterPro; IPR023057; GlnE.
DR InterPro; IPR005190; GlnE_rpt_dom.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR013546; PII_UdlTrfase/GS_AdlTrfase.
DR PANTHER; PTHR30621:SF0; BIFUNCTIONAL GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE_ADENYLYL-REMOVING ENZYME; 1.
DR PANTHER; PTHR30621; GLUTAMINE SYNTHETASE ADENYLYLTRANSFERASE; 1.
DR Pfam; PF08335; GlnD_UR_UTase; 2.
DR Pfam; PF03710; GlnE; 2.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 2.
DR SUPFAM; SSF81593; Nucleotidyltransferase substrate binding subunit/domain; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000313|EMBL:EKN00204.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:EKN00204.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006217};
KW Transferase {ECO:0000313|EMBL:EKN00204.1}.
FT DOMAIN 46..287
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 308..443
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
FT DOMAIN 555..784
FT /note="Glutamate-ammonia ligase adenylyltransferase
FT repeated"
FT /evidence="ECO:0000259|Pfam:PF03710"
FT DOMAIN 824..889
FT /note="PII-uridylyltransferase/Glutamine-synthetase
FT adenylyltransferase"
FT /evidence="ECO:0000259|Pfam:PF08335"
SQ SEQUENCE 948 AA; 101251 MW; 49CC4B6EBCE01F40 CRC64;
MPGDLHKPSF PKPADQAAAA RLRADFAALG PREAKLARSD SGAALLAALG GNAPFLAELA
CRESATLCAC LEAGPTPQAK AVLAGLASLP PDLPRAQLSD ALRRAKRQMA LSIAIADLGG
LWTLEQVTAA LSDLAETALR AAIRHLLYEL HAAEEIALPD PAAPDQGSGF VALALGKLGA
RELNYSSDID LVLLYDPESP VYGEDSQPMM ARLARDLTAL LAARDAEGYV FRVDLRLRPD
PGATPPVVAL ATALSYYESH GRTWERAAFS KARPVAGDLA LGQQFLAAIR PFIWRKYLDF
AAISDIHEMK RQIDAQHPAE GLRGFDVKLG QGGIREIEFI VQTLGLVWGG QDPALRIPAT
LEALPAMARA GHLPERAARQ LAADYRELRR VEHRLQMVAD RQTHALPASE AGLEAFCIFL
AAPRFRQSFP KLLARVHAHF LDFFDAGTQA LQDGLNPGPE GAPAPAFTAR LEALGFKDIK
HIAARLRDWG SGDMPALRSP RARELLDGLV APLLAALGAQ PEPDKAFAQF DTLLSRQRAG
VQLLSLFTRN PGLLKRLAAV LGAAPALSDY LTEDPQALDG LLAPEARFAA PRPVLRRLLA
EAEDLEQAAA ATRRFVRQEE FHLSVATLEG RLDANEAGRT RSALAEAALS QLLPLVIAAQ
KQRQPAPRGA KVAVLALGKA GAGEMLAGSD LDLMLIYDHA PMAIPPTQWF SRLSQAFVAA
LTAQGPGGPV YHVDMRLRPS GNAGPVAVSL ASFRSYHAKE SWTWERLALT RARVMAATPG
FAATVREAVL GALCRPEPRA RILADTAAMQ ARLAAEMKPR GPFDVRAIPG GMMEVGFIAQ
ALQLIHGGSE PALFQPNTEA ALKGLAAAGL LRQSDAEALI AADRLWRTIQ GINRITGLPL
SAAAPPGAML EPLLRATFFA DLAALQAGMR EAAAQAHQIF TQTFTEGA
//
