ID K6TJP3_9CLOT Unreviewed; 526 AA.
AC K6TJP3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Iron only hydrogenase large subunit {ECO:0000313|EMBL:EKQ51715.1};
GN ORFNames=A370_04700 {ECO:0000313|EMBL:EKQ51715.1};
OS Clostridium sp. Maddingley MBC34-26.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1196322 {ECO:0000313|EMBL:EKQ51715.1, ECO:0000313|Proteomes:UP000001325};
RN [1] {ECO:0000313|EMBL:EKQ51715.1, ECO:0000313|Proteomes:UP000001325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Maddingley MBC34-26 {ECO:0000313|Proteomes:UP000001325};
RX PubMed=23405323;
RA Rosewarne C.P., Greenfield P., Li D., Tran-Dinh N., Bradbury M.I.,
RA Midgley D.J., Hendry P.;
RT "Draft Genome Sequence of Clostridium sp. Maddingley, Isolated from Coal-
RT Seam Gas Formation Water.";
RL Genome Announc. 1:E00081-12(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKQ51715.1}.
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DR EMBL; ALXI01000154; EKQ51715.1; -; Genomic_DNA.
DR AlphaFoldDB; K6TJP3; -.
DR STRING; 1196322.A370_04700; -.
DR PATRIC; fig|1196322.3.peg.4564; -.
DR eggNOG; COG4624; Bacteria.
DR Proteomes; UP000001325; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:InterPro.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.20; -; 2.
DR Gene3D; 3.40.50.1780; -; 1.
DR Gene3D; 4.10.260.20; Iron hydrogenase, small subunit; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR008953; Fe_hydrogenase_HydB.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR InterPro; IPR036991; Fe_hydrogenase_ssu_sf.
DR PANTHER; PTHR11615:SF6; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR Pfam; PF14697; Fer4_21; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR SUPFAM; SSF48674; Fe-only hydrogenase smaller subunit; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 4.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001325}.
FT DOMAIN 14..44
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 55..84
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 387..416
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 417..446
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 526 AA; 58337 MW; 6B2EF1FAD927B718 CRC64;
MGKSKKNSRV QNDNIMQINK KKCIGCTACA FTCAKETKVA ILKEVNNGKK TVDPKQGSFG
DSGCIYCGQC AIACPTEAMS IRNDVELVKE ALNSGKYLVL ISSPSVKATL GEQFNLPIGT
YVGGKIAPSA KKLGFQNVFD TEFGADMVTV EESTELIKRI ANKERLPMFT SCCSAWIRYA
EHFHPEVLQY ISTSKSPQQL MGAGIKTYFA DTYNILPNNI VTVSVNSCAA KKYEAEREEM
GRNNYKDVDI VLTTSEYAEI LKEKGIDITA IPNEQTNPFM SEHTGAADIF GISGGAMNSI
LRTAANYLNS DISEVSRMQF NKVFGYDNIK EANISLGGQK YKVAVINGLR EIDGFLNSGK
WKDYLYIEVM ACRGGCVNGS GAPRIEKKSD INENLCIICG TCIENCPVNA IQYNVNGRAE
VQKEKCVGCK LCSNICRANA IKIQLYDKAT NSLIEKDYIK SRTDVLSDID IKSVKRVSDE
NERIHNMYKN YIGEPDGVKA NELLHTSYYD KSTHLQNRLD KKRKKH
//
