ID K6TQ07_9EURY Unreviewed; 474 AA.
AC K6TQ07;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Fe-S oxidoreductase {ECO:0000313|EMBL:EKQ54140.1};
GN ORFNames=B655_0941 {ECO:0000313|EMBL:EKQ54140.1};
OS Methanobacterium sp. Maddingley MBC34.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX NCBI_TaxID=1220534 {ECO:0000313|EMBL:EKQ54140.1, ECO:0000313|Proteomes:UP000001147};
RN [1] {ECO:0000313|EMBL:EKQ54140.1, ECO:0000313|Proteomes:UP000001147}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Maddingley MBC34 {ECO:0000313|Proteomes:UP000001147};
RX PubMed=23405289;
RA Rosewarne C.P., Greenfield P., Li D., Tran-Dinh N., Midgley D.J.,
RA Hendry P.;
RT "Draft Genome Sequence of Methanobacterium sp. Maddingley, Reconstructed
RT from Metagenomic Sequencing of a Methanogenic Microbial Consortium Enriched
RT from Coal-Seam Gas Formation Water.";
RL Genome Announc. 1:E00082-12(2013).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKQ54140.1}.
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DR EMBL; AMGN01000016; EKQ54140.1; -; Genomic_DNA.
DR AlphaFoldDB; K6TQ07; -.
DR STRING; 1220534.B655_0941; -.
DR PATRIC; fig|1220534.3.peg.935; -.
DR eggNOG; arCOG01356; Archaea.
DR Proteomes; UP000001147; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF17; MG-PROTOPORPHYRIN IX MONOMETHYL ESTER OXIDATIVE CYCLASE 66KD SUBUNIT; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485}.
FT DOMAIN 8..145
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 195..423
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 474 AA; 55146 MW; 7BECE1904A2FB402 CRC64;
MKVLFVEPPK VFWFVMGEYM PPPLGILQLA AYLEYRNDKW DIEVLDSQAM NYGWSKLQRH
IESTNPDIVV SSALATCNTF TVLRTLEIVK KVNPDIKTVV GGQHFTALAD ESLKKYPEID
FVVRGEGEVT LYELVKSLDE KTSPLDVKGL SFRNNDKIIH NPPRPFISNL DDLPFPGYHF
VEEHMKKYNF KMMAYKGAGY ALVEASRGCP HKCTFCSQWE HWGGKWRSKS PERIADEMEH
IYTEYGITFL WLTDDNFGLG KRTTKMCDEL IKRGLSDDIT WFLQARSDDI IKNQDNLPKM
RKAGNYWIMS GLERHDNEVL HDYHKGIKAS DAKLSVDLLK ENDIFSQATL ITGDRHDSHE
SIQKLRDFVN YVDPDLAIFM ILTPFPGTEL FETARKNEWL EDDNWANYDM VHAVMPTEHL
SRSEVQEELY LCYRSFYGSM RRRIGGLFSR NQFKRQTYRY MAGQGLLQAL RDLY
//
