ID   K6WUY6_9ACTN            Unreviewed;       340 AA.
AC   K6WUY6;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=1-deoxy-D-xylulose-5-phosphate synthase {ECO:0000313|EMBL:GAB90344.1};
GN   Name=dxs {ECO:0000313|EMBL:GAB90344.1};
GN   ORFNames=GORHZ_097_00200 {ECO:0000313|EMBL:GAB90344.1};
OS   Gordonia rhizosphera NBRC 16068.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC   Gordonia.
OX   NCBI_TaxID=1108045 {ECO:0000313|EMBL:GAB90344.1, ECO:0000313|Proteomes:UP000008363};
RN   [1] {ECO:0000313|EMBL:GAB90344.1, ECO:0000313|Proteomes:UP000008363}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 16068 {ECO:0000313|EMBL:GAB90344.1,
RC   ECO:0000313|Proteomes:UP000008363};
RA   Takarada H., Isaki S., Hosoyama A., Tsuchikane K., Katsumata H., Baba S.,
RA   Ohji S., Yamazaki S., Fujita N.;
RT   "Whole genome shotgun sequence of Gordonia rhizosphera NBRC 16068.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAB90344.1}.
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DR   EMBL; BAHC01000097; GAB90344.1; -; Genomic_DNA.
DR   AlphaFoldDB; K6WUY6; -.
DR   STRING; 1108045.GORHZ_097_00200; -.
DR   eggNOG; COG3958; Bacteria.
DR   Proteomes; UP000008363; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR   CDD; cd07033; TPP_PYR_DXS_TK_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR43825; PYRUVATE DEHYDROGENASE E1 COMPONENT; 1.
DR   PANTHER; PTHR43825:SF1; TRANSKETOLASE-LIKE PYRIMIDINE-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008363}.
FT   DOMAIN          34..198
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   340 AA;  36028 MW;  E0D23A361BF50F4E CRC64;
     MTATTTRPAG ASGTGKPKLR TSAMIASFAD PGQKTTPAPF GHALVAAARE NEKIVGLTAD
     LGKYTDMHIF AQEFPERFVQ VGMAEQLLFG AAAGMAETGL IPFASTYSVF AARRAYDFIC
     LDIAEPELNV NIVGGLPGLT TGYGPSHQAT EDMAIFRGMP NLTIVDPCDS VDIAAAVPQL
     ADHPGPTYLR LLRGQVPTVL DEYDYTFELG KAKVLRDGTD VVFVSSGLMT MRALLAAEAL
     AADNVSVAVV HSPTIKPFDA ETVLRELDTD RLAVTLENHS VTGGLFEATA AAVVRAGLGR
     QITPIALPDA FLDAGALPTL HDRYGLSTDR VRDRVLELLG
//