ID   K6YFR0_9ALTE            Unreviewed;       787 AA.
AC   K6YFR0;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=Signaling protein ykoW {ECO:0000313|EMBL:GAC15468.1};
GN   Name=ykoW {ECO:0000313|EMBL:GAC15468.1};
GN   ORFNames=GLIP_2847 {ECO:0000313|EMBL:GAC15468.1};
OS   Aliiglaciecola lipolytica E3.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Aliiglaciecola.
OX   NCBI_TaxID=1127673 {ECO:0000313|EMBL:GAC15468.1, ECO:0000313|Proteomes:UP000006334};
RN   [1] {ECO:0000313|EMBL:GAC15468.1, ECO:0000313|Proteomes:UP000006334}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E3 {ECO:0000313|EMBL:GAC15468.1,
RC   ECO:0000313|Proteomes:UP000006334};
RX   PubMed=25009843;
RA   Qin Q.-L., Xie B.-B., Yu Y., Shu Y.-L., Rong J.-C., Zhang Y.-J.,
RA   Zhao D.-L., Chen X.-L., Zhang X.-Y., Chen B., Zhou B.-C., Zhang Y.-Z.;
RT   "Comparative genomics of the marine bacterial genus Glaciecola reveals the
RT   high degree of genomic diversity and genomic characteristic for cold
RT   adaptation.";
RL   Environ. Microbiol. 16:1642-1653(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAC15468.1}.
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DR   EMBL; BAEN01000056; GAC15468.1; -; Genomic_DNA.
DR   AlphaFoldDB; K6YFR0; -.
DR   STRING; 1127673.GLIP_2847; -.
DR   eggNOG; COG5001; Bacteria.
DR   OrthoDB; 8553030at2; -.
DR   Proteomes; UP000006334; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR029150; dCache_3.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF84; SIGNALLING PROTEIN WITH EAL DOMAIN; 1.
DR   Pfam; PF14827; dCache_3; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006334};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        260..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          382..515
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          524..778
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   COILED          317..347
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   787 AA;  89413 MW;  F1D0FEEFD728210A CRC64;
     MSFLWLQKTN QDLLLKQQEI KHQNQSQYLL LNKMFRSRNE SWVEMLVQLH QDQPQAILAL
     AHSLSKRLVF LQYNMQVEKV WLFDGSKNLV FSSEPDIPEH IKTNTDYVLE NQDSKEITYC
     SIQCTQVLSI PILHSDDSMA VITLSLTLVD TLAFLNQSTD ATLALVYVKE KPDTLYARDF
     LKHEPLATKH KNLINSIISA FPKDLSVDAL ASSGAQLSID EKHYFVALIP MSTVNSDHDY
     VLAAHDITPM VLAHLAYQKN ILMTASVVFV VAMLLFYLIT NSVRQRLVDF TARLPLLASR
     DYQQFRSRSR ISKHYFVDEL DTLNDSANKL ADRLEKLDNE VLTKANELEK MAMFDQLTSL
     PNRNMLVIKT KQAVAKLGNE DKFVVLMVFD LDDFKKVNDS YGHTIGDELL REAAARFQSV
     LKDHDLACRL GGDEFAILLS DVDDIKSAME VAEKLVDRFR APINVAQLRF YVSTSVGFAY
     TSSSDANVNE LIRCADIAMY QAKNHGGNRL ELYVDSMSKN AIDKVALEDE ARSALINDHF
     SYSLQPQVEL KTGRLVGFEA LLRWNHPDRG PVSPGYFIPI LENTEFMLTL GYWCIENAFN
     LLNAFKQHGY PNLKIAINLA AIQFLDPDLV PYLEEKVKES GLAPDLIELE LTERTLVSDI
     QRTTEIMQTL IDKGFLISID DFGTGYSSLS YLKTMPANFI KIDRAFIDGM LTNDADKQIV
     AATVSMVQNL KMKVIAEGIE EQLQIDLLKQ FDCNMAQGFY IAKPIPEDLL FEELQKYCKD
     GIWQYGQ
//