ID K7B162_PANTR Unreviewed; 212 AA.
AC K7B162; A0A2J8KAJ4;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=RAB43, member RAS onco family {ECO:0000313|Ensembl:ENSPTRP00000081260.1};
DE SubName: Full=RAB43, member RAS oncogene family {ECO:0000313|EMBL:JAA13913.1};
GN Name=RAB43 {ECO:0000313|EMBL:JAA13913.1,
GN ECO:0000313|Ensembl:ENSPTRP00000081260.1,
GN ECO:0000313|VGNC:VGNC:57652};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA13913.1};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000081260.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA13913.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA06974.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA34554.1}, Skin {ECO:0000313|EMBL:JAA29330.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA13913.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000081260.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004423}; Lipid-
CC anchor {ECO:0000256|ARBA:ARBA00004423}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004423}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270}.
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DR EMBL; AACZ04048149; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01004364; JAA06974.1; -; mRNA.
DR EMBL; GABF01008232; JAA13913.1; -; mRNA.
DR EMBL; GABD01003770; JAA29330.1; -; mRNA.
DR EMBL; GABE01010185; JAA34554.1; -; mRNA.
DR RefSeq; XP_009444694.1; XM_009446419.2.
DR STRING; 9598.ENSPTRP00000081260; -.
DR Ensembl; ENSPTRT00000084494.1; ENSPTRP00000081260.1; ENSPTRG00000050264.1.
DR GeneID; 100615763; -.
DR KEGG; ptr:100615763; -.
DR CTD; 339122; -.
DR VGNC; VGNC:57652; RAB43.
DR GeneTree; ENSGT00940000161980; -.
DR OMA; FIERHGN; -.
DR OrthoDB; 8685at2759; -.
DR Proteomes; UP000002277; Chromosome 3.
DR Bgee; ENSPTRG00000050264; Expressed in liver and 21 other cell types or tissues.
DR GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045335; C:phagocytic vesicle; IEA:Ensembl.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0000045; P:autophagosome assembly; IBA:GO_Central.
DR GO; GO:0071346; P:cellular response to type II interferon; IEA:Ensembl.
DR GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0090382; P:phagosome maturation; IEA:Ensembl.
DR GO; GO:0035526; P:retrograde transport, plasma membrane to Golgi; IEA:Ensembl.
DR GO; GO:0019068; P:virion assembly; IEA:Ensembl.
DR CDD; cd01864; Rab19; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048040; Rab19/43.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47979; DRAB11-RELATED; 1.
DR PANTHER; PTHR47979:SF117; RAB43, MEMBER RAS ONCOGENE FAMILY; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 2: Evidence at transcript level;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
SQ SEQUENCE 212 AA; 23339 MW; 087EE3802B7159C9 CRC64;
MAGPGPGPGD PDEQYDFLFK LVLVGDASVG KTCVVQRFKT GAFSERQGST IGVDFTMKTL
EIQGKRVKLQ IWDTAGQERF RTITQSYYRS ANGAILAYDI TKRSSFLSVP HWIEDVRKYA
GSNIVQLLIG NKSDLSELRE VSLAEAQSLA EHYDILCAIE TSAKDSSNVE EAFLRVATEL
IMRHGGPLFS EKSPDHIQLN SKDIGEGWGC GC
//
