ID K7B1U7_PANTR Unreviewed; 1085 AA.
AC K7B1U7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 13-SEP-2023, entry version 41.
DE SubName: Full=Importin 4 {ECO:0000313|EMBL:JAA14138.1};
GN Name=IPO4 {ECO:0000313|EMBL:JAA14138.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA14138.1};
RN [1] {ECO:0000313|EMBL:JAA14138.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Smooth vascular {ECO:0000313|EMBL:JAA14138.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; GABF01008007; JAA14138.1; -; mRNA.
DR AlphaFoldDB; K7B1U7; -.
DR OrthoDB; 22606at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF6; IMPORTIN-4; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 2.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 2: Evidence at transcript level;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 24..90
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 395..435
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 904..942
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 1085 AA; 119168 MW; 839C2D64AD3E6D06 CRC64;
MEPAGLERLL RELLLPDTER IRRATEQLQI VLRAPAALPA LCDLLASAAD PQIRQFAAVL
TRRRLNTRWR RLAAEQRESL KSLILTALQR ETEHCVSLSL AQLSATIFRK EGLEAWPQLL
QLLQHSTHSP HSPEREMGLL LLSVVVTSRP EAFQPHHREL LRLLNETLGE VGSPGLLFYS
LRTLTTMAPY LSTEDVPLAR MLVPKLIMAV QTLIPIDEAK ACEALEALDE LLESEVPVIT
PYLSEVLTFC LEVARNVALG NAVRVRILCC LAFLVKVKSK ALLKNRLLPP LLHTLFPIMA
AEPPPGQLDP EDQDSEEEEL EIELMGETPK HFAVQVRCGV VDMLALHLPP EKLCPQLMPM
LEEALRSESP YQRKAGLLVL AVLSDGAGNH IRQRLLPPLL QIVCKGLEDP SQVVRNAALF
ALGQFSENLQ PHISSYSREV MPLLLAYLKS VPLGHTHHLA KACYALENFV ENLGPKVQPY
LPELMECMLQ LLRNPSSPRA KELAVSALGA IATAAQASLL PYFPAIMEHL REFLLTGRED
LQPVQIQSLE TLGVLARAVG EPMRPLAEEC CQLGLGLCDQ VDDPDLRRCT YSLFAALSGL
MGEGLAPHLE QITTLMLLSL RSTEGIVPQY DGSSSFLLFD DESDGEEEEE LMDEDVEEED
DSEISGYSVE NAFFDEKEDT CAAVGEISVN TSVAFLPYME SVFEEVFKLL ECPHLNVRKA
AHEALGQFCC ALHKACQSCP SEPNTAALQA ALARVVPSYM QAVNRERERQ VVMAVLEALT
GVLRSCGTLT LKPPGRLAEL CGVLKAVLQR KTACQDTDEE EEEEDDDQAE YDTMLLEHAG
EAIPALAAAA GGDSFAPFFA GFLPLLVCKT KQGCTVAEKS FAVGTLAETI QGLGAASAQF
VSRLLPVLLS TAREADPEVR SNAIFGMGVL AEHGGHPAQE HFPKLLGLLF PLLARERHDR
VRDNICGALA RLLMASPTRK PEPQVLAALL HALPLKEDLE EWVTIGRLFS FLYQSSPDQV
IDVAPELLRI CSLILADNKI PPDTKAALLL LLTFLAKQHT DSFQAALGSL PVDKAQELQA
VLGLS
//
