ID K7BWM3_PANTR Unreviewed; 271 AA.
AC K7BWM3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Abhydrolase domain containing 14A {ECO:0000313|EMBL:JAA34671.1, ECO:0000313|Ensembl:ENSPTRP00000092430.1};
GN Name=ABHD14A {ECO:0000313|EMBL:JAA34671.1,
GN ECO:0000313|Ensembl:ENSPTRP00000092430.1,
GN ECO:0000313|VGNC:VGNC:57671};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA34671.1};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000092430.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA34671.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAA34671.1}, Skin
RC {ECO:0000313|EMBL:JAA26693.1}, and Smooth vascular
RC {ECO:0000313|EMBL:JAA15503.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000092430.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. ABHD14 family.
CC {ECO:0000256|ARBA:ARBA00037942}.
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DR EMBL; AACZ04000326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABF01006642; JAA15503.1; -; mRNA.
DR EMBL; GABD01006407; JAA26693.1; -; mRNA.
DR EMBL; GABE01010068; JAA34671.1; -; mRNA.
DR Ensembl; ENSPTRT00000077149.1; ENSPTRP00000092430.1; ENSPTRG00000043627.1.
DR VGNC; VGNC:57671; ABHD14A.
DR GeneTree; ENSGT00940000161296; -.
DR OMA; GWSFNAD; -.
DR Proteomes; UP000002277; Chromosome 3.
DR Bgee; ENSPTRG00000043627; Expressed in dorsolateral prefrontal cortex and 20 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR PANTHER; PTHR46197:SF1; PROTEIN ABHD14A; 1.
DR PANTHER; PTHR46197; PROTEIN ABHD14B-LIKE; 1.
DR Pfam; PF12697; Abhydrolase_6; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 2: Evidence at transcript level;
KW Hydrolase {ECO:0000313|EMBL:JAA34671.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 97..194
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF12697"
SQ SEQUENCE 271 AA; 29966 MW; E6839D0CB6E52B91 CRC64;
MVGALCGCWF RLGGARPLIP FGPTVVQTSM SRSQVALLGL SLLLMLLLYV GLPGPPEQTS
WLWGDPNVTV LAGLTPGNSP IFYREVLPLN QAHRVEVVLL HGKAFNSHTW EQLGTLQLLS
QRGYRAVALD LPGFGNSAPS KEASTEAGRA VLLERVLRDL EVQNAVLVSP SLSGHYALPF
LMRGHHQLHG FVPIAPTSTQ NYTQEQFWAV KTPTLILYGE LDHILARESL RRLRHLPNHS
VVKLRNAGHA CYLHKPQDFH LVLLAFLDHL P
//
