ID K7BXR4_PANTR Unreviewed; 516 AA.
AC K7BXR4;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Tripartite motif containing 6 {ECO:0000313|EMBL:JAA35086.1, ECO:0000313|Ensembl:ENSPTRP00000072660.1};
GN Name=TRIM6 {ECO:0000313|EMBL:JAA35086.1, ECO:0000313|VGNC:VGNC:946};
GN Synonyms=TRIM34 {ECO:0000313|Ensembl:ENSPTRP00000072660.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA35086.1};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000072660.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA35086.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAA35086.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000072660.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AACZ04016645; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04016646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04016647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABE01009653; JAA35086.1; -; mRNA.
DR RefSeq; XP_009458039.2; XM_009459764.2.
DR PaxDb; 9598-ENSPTRP00000040353; -.
DR Ensembl; ENSPTRT00000082415.1; ENSPTRP00000072660.1; ENSPTRG00000003257.7.
DR GeneID; 100568282; -.
DR CTD; 117854; -.
DR VGNC; VGNC:946; TRIM6.
DR GeneTree; ENSGT00940000162320; -.
DR OrthoDB; 3453019at2759; -.
DR Proteomes; UP000002277; Chromosome 11.
DR Bgee; ENSPTRG00000003257; Expressed in testis and 22 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19761; Bbox2_TRIM5-like; 1.
DR CDD; cd16591; RING-HC_TRIM5-like_C-IV; 1.
DR CDD; cd15823; SPRY_PRY_TRIM6; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR035828; PRY/SPRY_TRIM6.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF51; TRIPARTITE MOTIF-CONTAINING PROTEIN 6; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 43..88
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 120..161
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 310..516
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 165..196
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 230..264
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 516 AA; 59454 MW; 3D84C60E3552EC72 CRC64;
MCGSERILQA GNILEIRVGQ AGARRVATMT SPVLVDIREE VTCPICLELL TEPLSIDCGH
SFCQACITPN SRESVIGQEG ERSCPVCQTS YQPGNLRPNR HLANIVRRLR EVVLGPGKQL
KAVLCADHGE KLQLFCQEDG KVICWLCERS QEHRGHHTFL VEEVAREYQE KFQESLKKLK
NEEQEAEKLT AFIREKKTSW KNQMDPERCR IQTEFNQLRN ILDRVEQREL KKLEQEEKKG
LRIIEEAEND LVHQTQSLRE LISDLERRCQ GSAMELLQDV SDVTERSEFW TLRKPEALPT
KLRSMFRAPD LKRMLRVFRE LTDVQSYWVD VTLNPHTANL NLVLAKNRRQ VRFVGAKVSG
PSCLEKHYDC SVLGSQHFSS GKHYWEVDVA KKTAWILGVC SNSLGPTFSF NHYAQNHSAY
SRYQPQSGYW VIGLQHNHEY RAYEDSSPSL LLSMTVPPRR VGVFLDYEAG TVSFYNVTNH
GFPIYTFSKY YFPTTLCPYF NPCNCVIPMT LRRPNS
//
