ID K7DM07_PANTR Unreviewed; 723 AA.
AC K7DM07; A0A2J8NIG1;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};
GN Name=OSBPL9 {ECO:0000313|EMBL:JAA36347.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA36347.1};
RN [1] {ECO:0000313|EMBL:JAA36347.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAA36347.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the OSBP family.
CC {ECO:0000256|RuleBase:RU003844}.
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DR EMBL; GABE01008392; JAA36347.1; -; mRNA.
DR AlphaFoldDB; K7DM07; -.
DR SMR; K7DM07; -.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13290; PH_ORP9; 1.
DR Gene3D; 1.10.287.2720; -; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR018494; Oxysterol-bd_CS.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10972:SF102; OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9; 1.
DR Pfam; PF01237; Oxysterol_BP; 2.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01013; OSBP; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055,
KW ECO:0000256|RuleBase:RU003845};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003845}.
FT DOMAIN 2..99
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 218..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 668..695
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 237..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 723 AA; 81787 MW; 78932D752B0723F6 CRC64;
MASIMEGPLS KWTNVMKGWQ YRWFVLDYNA GLLSYYTSKD KMMRGSRRGC VRLRGAVIGI
DDEDDSTFTI TVDQKTFHFQ ARDADEREKW IHALEETILR HTLQLQGLDS GFVPSVQDFD
KKLTEADAYL QILIEQLKLF DDKLQNCKED EQRKKIETLK ETTNSMVESI KHCIVLLQIA
KSTINPVDAI YQPSPLEPVI STMPSQTVLP PEPVQLCKSE QRPSSLPVGP VLATLGHHQT
PTPNSTGSGH SPPSSSLTSP SHVNLSPNTV PEFSYSSSED EFYDADEFHQ SGSSPKRLID
SSGSASVLTH SSSGNSLKRP DTTESLNSSL SNGTSDADLF DSHDDRDDDA EAGSVEEHKS
VIMHLLSQVR LGMDLTKVVL PTFILERRSL LEMYADFFAH PDLFVSISDQ KDPKDRMVQV
VKWYLSAFHA GRKGSVAKKP YNPILGEIFQ CHWTLPNDTE ENTELVSEGP VPWVSKNSVT
FVAEQVSHHP PISAFYAECF NKKIQFNAHI WTKSKFLGMS IGVHNIGQGC VSCLDYDEHY
ILTFPNGYGR SILTVPWVEL GGECNINCSK TGYSANIIFH TKPFYGGKKH RITAEIFSPN
DKKSFCSIEG EWNGVMYAKY ATGENTVFVD TKKLPIIKKK VRKLEDQNEY ESRSLWKDVT
FNLKIRDIDA ATEAKHRLEE RQRAEARERK EKEIQWETRL FHEDGECWVY DEPLLKRLGA
AKH
//
