ID   K7DSF1_PANTR            Unreviewed;       480 AA.
AC   K7DSF1;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   08-NOV-2023, entry version 37.
DE   SubName: Full=Solute carrier family 29 (Nucleoside transporters), member 1 {ECO:0000313|EMBL:JAA41407.1};
GN   Name=SLC29A1 {ECO:0000313|EMBL:JAA41407.1};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA41407.1};
RN   [1] {ECO:0000313|EMBL:JAA41407.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Skeletal muscle {ECO:0000313|EMBL:JAA41407.1};
RA   Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT   "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT   mRNA sequences.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Apical cell membrane
CC       {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004424}. Basolateral cell membrane
CC       {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004554}. Lateral cell membrane
CC       {ECO:0000256|ARBA:ARBA00034693}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00034693}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC       {ECO:0000256|ARBA:ARBA00007965}.
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DR   EMBL; GABE01003332; JAA41407.1; -; mRNA.
DR   AlphaFoldDB; K7DSF1; -.
DR   GO; GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015213; F:uridine transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR034764; ENT1/ENT2.
DR   InterPro; IPR002259; Eqnu_transpt.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   NCBIfam; TIGR00939; 2a57; 1.
DR   PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR   PANTHER; PTHR10332:SF9; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; 1.
DR   Pfam; PF01733; Nucleoside_tran; 1.
DR   PIRSF; PIRSF016379; ENT; 1.
DR   PRINTS; PR01130; DERENTRNSPRT.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   2: Evidence at transcript level;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        37..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        160..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        205..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        229..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        313..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        389..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        418..442
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        454..476
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          278..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   480 AA;  52650 MW;  3F27E4ED80C12CEF CRC64;
     MLTPKSQAPE GGSCQPGKTE NTITMTTSHQ PQDRYKAVWL IFFMLGLGTL LPWNFFMTAT
     QYFTNRLDMS QNVSLVTAEL SKDAQASAAP AAPLPERNSL SAIFNNVMTL CAMLPLLLFT
     YLNSFLHQRI PQSVRILGSL VAILLVFLIT AILVKVQLDA LPFFVITMIK IVLINSFGAI
     LQGSLFGLAG LLPASYTAPI MSGQGLAGFF ASVAMICAIA SGSELSESAF GYFITACAVI
     ILTIICYLGL PRLEFYRYYQ QLKLEGPGEQ ETKLDLISKG EEPRAGKEES GVSVSNSQPT
     SESHSIKAIL KNISVLAFSV CFIFTITIGM FPAVTVEVKS SIAGSSTWER YFIPVSCFLT
     FNIFDWLGRS LTAVFMWPGK DSRWLPSLVL ARLVFVPLLL LCNIKPRRYL TVVFEHDAWF
     IFFMAAFAFS NGYLASLCMC FGPKKVKPAE AETAGAIMAF FLCLGLALGA VFSFLFRAIV
//