ID K7EJG5_HUMAN Unreviewed; 71 AA.
AC K7EJG5;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=ECSIT signaling integrator {ECO:0000313|Ensembl:ENSP00000465162.1};
DE Flags: Fragment;
GN Name=ECSIT {ECO:0000313|Ensembl:ENSP00000465162.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000465162.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000465162.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0007829|PubMed:21269460}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [3] {ECO:0007829|PubMed:25944712}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=25944712;
RA Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D.,
RA Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT "N-terminome analysis of the human mitochondrial proteome.";
RL Proteomics 15:2519-2524(2015).
RN [4] {ECO:0000313|Ensembl:ENSP00000465162.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC008481; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR MassIVE; K7EJG5; -.
DR PeptideAtlas; K7EJG5; -.
DR Ensembl; ENST00000592571.1; ENSP00000465162.1; ENSG00000130159.15.
DR UCSC; uc060ttu.1; human.
DR HGNC; HGNC:29548; ECSIT.
DR VEuPathDB; HostDB:ENSG00000130159; -.
DR GeneTree; ENSGT00390000005147; -.
DR HOGENOM; CLU_2764426_0_0_1; -.
DR ChiTaRS; ECSIT; human.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000130159; Expressed in apex of heart and 193 other cell types or tissues.
DR ExpressionAtlas; K7EJG5; baseline and differential.
DR InterPro; IPR010418; ECSIT.
DR InterPro; IPR046448; ECSIT_N.
DR PANTHER; PTHR13113; ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS; 1.
DR PANTHER; PTHR13113:SF1; EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL; 1.
DR Pfam; PF06239; ECSIT_N; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:K7EJG5,
KW ECO:0007829|MaxQB:K7EJG5};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 2..41
FT /note="ECSIT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06239"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000465162.1"
SQ SEQUENCE 71 AA; 7858 MW; 34299FB764B6ED99 CRC64;
XVNPFPVPRD LPQDPVELAM FGLRHMEPDL SARVTIYQAP CAAPDAARLP PQRFLCPKTQ
QVQQIPPSPT S
//
