ID K7F7X6_PELSI Unreviewed; 1299 AA.
AC K7F7X6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Gem nuclear organelle associated protein 5 {ECO:0000313|Ensembl:ENSPSIP00000004136.1};
GN Name=GEMIN5 {ECO:0000313|Ensembl:ENSPSIP00000004136.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000004136.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000004136.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGCU01197043; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01197044; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_014436638.1; XM_014581152.1.
DR STRING; 13735.ENSPSIP00000004136; -.
DR Ensembl; ENSPSIT00000004159.1; ENSPSIP00000004136.1; ENSPSIG00000003898.1.
DR eggNOG; ENOG502QPYZ; Eukaryota.
DR GeneTree; ENSGT00620000088064; -.
DR HOGENOM; CLU_004491_0_1_1; -.
DR OMA; YWFNRND; -.
DR TreeFam; TF328886; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016604; C:nuclear body; IEA:Ensembl.
DR GO; GO:0032797; C:SMN complex; IEA:Ensembl.
DR GO; GO:0034718; C:SMN-Gemin2 complex; IEA:Ensembl.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; IEA:Ensembl.
DR GO; GO:0043022; F:ribosome binding; IEA:Ensembl.
DR GO; GO:0000340; F:RNA 7-methylguanosine cap binding; IEA:Ensembl.
DR GO; GO:0030619; F:U1 snRNA binding; IEA:Ensembl.
DR GO; GO:0030621; F:U4 snRNA binding; IEA:Ensembl.
DR GO; GO:0030622; F:U4atac snRNA binding; IEA:Ensembl.
DR GO; GO:0006417; P:regulation of translation; IEA:Ensembl.
DR GO; GO:0000387; P:spliceosomal snRNP assembly; IEA:Ensembl.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46362; GEM-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR46362:SF1; GEM-ASSOCIATED PROTEIN 5; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 2.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 11..34
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 313..361
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 408..442
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 490..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..621
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1094..1137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1199..1219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 593..616
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1094..1113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1122..1137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1299 AA; 144370 MW; 8EA9FB30B6634C6C CRC64;
MQEAALMKGC YLASGSKDQT IRIWSCARGR GVMTLKLPTL KRRSGGIDPA IKERIWLTVH
WPCGHPTEIV SSCFGGELLL WDLSQSGKRK WTLLGSSSEG QNHTRIVFNL CSVQALGREL
LLSISMDRDV KCWDLTTLDC SWTLPSLGGF VYSLAFSPVD TGCLAIGVGD SMIRVWNTLS
MSNTYDVKTL WQGIKSKVTA LSWHPTKEGC LAFGTDDGKV GVYDTYSSNI KNRPPQISST
YHKKTVYTLA WGPPTPPLSF GGDGDRPSVT LYSCAGEGIV LQHNPWKFSG EANDINKVIR
DTNSIKYKLP ARTEISWKPD GKFLALGNED GSIEIFQAPN LKLLCTIQQH HKLINAIRWH
HEHGTQPELS YMIASGSINA VIYVHNLKSI IESPSKTPVT ITEPFRTLVG HTAKITSLSW
SPHHEGRLVS ACYDGTAQVW DVLKEEPLCN YRGHRGRLLC VQWSPVDPDS VYTGADDFCV
HKWLTSKQEY TRPPQGKKSI DLEKKRSSQP KPKAKKKKKP MGKVPAKQDV SDTVNGDEIV
DSLLDENGIS DHEEEKESQE FSDKISLAVP KEPPLHPRVC SVFDVPKPFM NHKTTPGKKD
HPKDKPVPDA SMKKRKPRSI LPISTSMDQR SKDELHQDCL TLATCLRSKG LNEGLAQDSG
DHIHLGMFTD RPALYRLMEV EGKSHLENGH SELFQQLMLW KGDLKGILQS AAERGELTDQ
LVAVSPMAGY QAWVWTVEAF AKQLCFQEQY VKAASHLLSI HKVYEAVELL KTNHFYREAI
VIAKARLRPE DPVLKDLYTS WAAVLEKDGH YSTAAKCYLG ATSPYDAVKV LAKKGDVASL
KTAAELAQIV GEKDLATTFS FRCAQELLSA RNWVGAQEVL QRQESLLGQR LVFCLNELLC
KCLSERNPTE RKSCFLPCYH SWVVRTQGSF VEMVSEVWRS AFGVGTAEQA KAVFEQLQGI
EYPPATSNTH PKQLLLHVSH DLTLAVLSHE TASWDEAVKA LLRAVTRSYD AGNFTLMQEV
CRLLLPKGCD HLRDNLDSTN IQSVAACRSL EGFVAYALLY DLWWNLPKDS HVSVQAAPDS
VPCPSEQTAV DQSDLSAASC SEETANQTAA AVGKNLPSAD HNHSRTESNS TASVSDLGER
QLKLNGCKML LSEGHAALQS SQKDVTEVQQ TLADMIRQHQ RNNLQESIKD GGTQEIKLES
DGLEPPSSQS PCKEAAKEPV SLPELMKRLT EANEKLAEFP ENLKAFPFPD VLECGLVLLH
IGAQCPTELN PELQQQALDL LRKYSRAEVY EKICRKFLT
//
