ID K7FEV4_PELSI Unreviewed; 617 AA.
AC K7FEV4;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Formin binding protein 1 {ECO:0000313|Ensembl:ENSPSIP00000006564.1};
GN Name=FNBP1 {ECO:0000313|Ensembl:ENSPSIP00000006564.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000006564.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000006564.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cell cortex
CC {ECO:0000256|ARBA:ARBA00004544}.
CC -!- SIMILARITY: Belongs to the FNBP1 family.
CC {ECO:0000256|ARBA:ARBA00009426}.
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DR EMBL; AGCU01121699; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01121700; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01121701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01121702; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01121703; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01121704; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01121705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01121706; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01121707; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01121708; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006128407.1; XM_006128345.2.
DR AlphaFoldDB; K7FEV4; -.
DR STRING; 13735.ENSPSIP00000006564; -.
DR Ensembl; ENSPSIT00000006601.1; ENSPSIP00000006564.1; ENSPSIG00000005955.1.
DR GeneID; 102451364; -.
DR KEGG; pss:102451364; -.
DR CTD; 23048; -.
DR eggNOG; KOG3565; Eukaryota.
DR GeneTree; ENSGT00950000183047; -.
DR HOGENOM; CLU_023320_2_0_1; -.
DR OMA; XQNEGTI; -.
DR OrthoDB; 2995634at2759; -.
DR TreeFam; TF351162; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07676; F-BAR_FBP17; 1.
DR CDD; cd11629; HR1_FBP17; 1.
DR Gene3D; 6.10.140.470; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR037449; FNBP1_F-BAR.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR PANTHER; PTHR15735:SF13; FORMIN-BINDING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS51860; REM_1; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..264
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 404..481
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 550..611
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 294..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 411..438
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 336..351
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 617 AA; 71393 MW; EA5673A06A0E01A3 CRC64;
MSWGTELWDQ FDNLEKHTQW GIDVLEKYIK FVKERTEIEI SYAKQLRNLS KKYQPKKNSK
EEEEYKYTSC KAFLVTLNEM NDYAGQHEVI SENMTSQITA ELTRYMQELK QERKSYFHDG
RKAQQYIETC WKQLEASKRR FERDCKEADR AQQYFEKMDA DINVTKADVE KARQQAQIRH
QMAEDSKAEY SSSLQKFNHE QHEHYHTHIP NIFQKIQEME ERRIVRIGEC MKTYAEVDRQ
VIPIIGKCLD GITKAAESID QKNDSQLVIE AFKSGFEPPG DIDFEDFTQP MKRTVSETSL
SNSRGDGKSE PKFGGKSKGK LWPFIKKNKL MSLLTSPHQP PPPPPASASP SAVPNGPQSP
KQQKEPLSHR FNEFMTSKPK IHCFRSLKRG LSLKLGGGPE DFSNLPPEQR RKKLQQKVDE
LNKDIQKEMD QRDALTKMKD VYIKNPQMGD AASVDYKLAE LGQNMEKLRL EAQKFEGWLA
EVEGRLPVRT EQSRRQSGMY ETQNTSAVNN CAQDRESPDG SYTEEQSQES EMKVPMTEFD
DEFDDEEPLP TIGTCKALYT FEGQNEGTIS VAEGELLYVI EEDKGDGWTR IRRNENEEGY
VPTSYVEVYL DKNAKDS
//
