ID K7FF22_PELSI Unreviewed; 477 AA.
AC K7FF22;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Butyrophilin subfamily 1 member A1 {ECO:0008006|Google:ProtNLM};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000006632.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000006632.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG family.
CC {ECO:0000256|ARBA:ARBA00007591}.
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DR EMBL; AGCU01151530; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01151531; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01151532; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01151533; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01151534; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01151535; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01151536; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FF22; -.
DR Ensembl; ENSPSIT00000006669.1; ENSPSIP00000006632.1; ENSPSIG00000006068.1.
DR eggNOG; ENOG502QSRZ; Eukaryota.
DR GeneTree; ENSGT00940000153527; -.
DR HOGENOM; CLU_013137_22_2_1; -.
DR OMA; WVKMIPE; -.
DR TreeFam; TF331083; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd05713; IgV_MOG_like; 1.
DR CDD; cd12888; SPRY_PRY_TRIM7_like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF145; BUTYROPHILIN SUBFAMILY 1 MEMBER A1; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF07686; V-set; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00409; IG; 1.
DR SMART; SM00406; IGv; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..477
FT /note="Butyrophilin subfamily 1 member A1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003901638"
FT TRANSMEM 232..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..128
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 134..220
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 308..477
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 477 AA; 53489 MW; 7C5439413F6F4748 CRC64;
LSVFLFRVFW CIAQFKVLGP DQPVTAVVDG EIVLLCHLNP RKNAENMEVT WFRSQLSPFV
HRYSAGKDEY GQQMPEYQGR TELLRDGLPS GSVALRISRV RLSDEGQYSC FVQDGSNYEE
ALLELKVAAS GSAPHISVED YQDGGIRVVC RSARWYPEPE VLWRDHRGQP LPSFSPTKTQ
VASHLYEIQT SIIITEDSNP NFSCLVRNTR LSQEKESTLF YPKPFFPRVN PWIVVTCVVL
VALAGSFGLS AYFFKIKDQC VVQDTLVSRM QKTVTFACTD RESGMDLKGG NEAMERQAAE
LRKCHSSLAT CRWKLFLLPP LPLPAAKVTL DPNTAHRNLI LSQDGKHVSW AGTRQDLPDN
PERFDTDLSV LCCEGFASGT HCWEVEAKVG DGIYWAVGVA RESVGRKGKM SHKPEEGIWA
VKWWGDHIKV LTSPETLLPL KQAPSRIRVC LDCDRGQVAF FDADAKAQIF TFPPGSI
//
