ID K7FJD8_PELSI Unreviewed; 1606 AA.
AC K7FJD8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=G protein-coupled receptor 179 {ECO:0000313|Ensembl:ENSPSIP00000008148.1};
GN Name=GPR179 {ECO:0000313|Ensembl:ENSPSIP00000008148.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000008148.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000008148.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Postsynaptic
CC cell membrane {ECO:0000256|ARBA:ARBA00034104}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00034104}. Synaptic cell membrane
CC {ECO:0000256|ARBA:ARBA00034099}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00034099}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family.
CC {ECO:0000256|ARBA:ARBA00007242}.
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DR EMBL; AGCU01094063; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01094064; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01094065; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01094066; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01094067; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01094068; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01094069; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01094070; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01094071; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01094072; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 13735.ENSPSIP00000008148; -.
DR Ensembl; ENSPSIT00000008191.1; ENSPSIP00000008148.1; ENSPSIG00000007458.1.
DR eggNOG; KOG4418; Eukaryota.
DR GeneTree; ENSGT00940000160776; -.
DR HOGENOM; CLU_244093_0_0_1; -.
DR OMA; KAELCPW; -.
DR TreeFam; TF319114; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0044292; C:dendrite terminus; IEA:Ensembl.
DR GO; GO:0045211; C:postsynaptic membrane; IEA:Ensembl.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0072659; P:protein localization to plasma membrane; IEA:Ensembl.
DR GO; GO:0009416; P:response to light stimulus; IEA:Ensembl.
DR GO; GO:0007601; P:visual perception; IEA:Ensembl.
DR CDD; cd15293; 7tmC_GPR158-like; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR043458; GPR158/179.
DR PANTHER; PTHR32546; G-PROTEIN COUPLED RECEPTOR 158-RELATED; 1.
DR PANTHER; PTHR32546:SF16; G-PROTEIN COUPLED RECEPTOR CG31760-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 299..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 297..547
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT REGION 615..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 881..903
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 920..1191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1226..1264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1297..1326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1340..1439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1458..1531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1579..1606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..632
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..694
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 968..1007
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1017..1037
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1056..1070
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1104..1118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1149..1179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1397..1439
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1460..1498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1499..1517
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1606 AA; 176739 MW; BCB7D1AC3F295D23 CRC64;
GPPPSLRATL RGATEALSHA TNFLNMLFQT NDIRESSVKE DTEWYHALVR SLVEGDPQVY
RAVLTFHAHP ASAKPQLVLQ ASKENNEILL QELSAEGPRN GSGEGQGFPG PLAPPGLSLR
KRVLVNDLKS LHTPKWHRGD SYVMDASHVR WSPPFLECQD SKFLPSWMVA LSSAFYGLKP
DLSPEFKGVV RMDVKLQDVE INPCASSPGW FTATHQCDLN STQCVPQESR GFVLGSHLLT
FPPVFFLPAD PEGSSARDAG QDGAATAGSL LACWPCREGC VTCVDDSPCL IQEDWPLRAA
VLAFQAFCML AVFLSMLVSY HFRKSKRIRA SGVILLETIL FGSLLLYFPV FILYFKPSIF
RCIVLRWVRM LGFAIVYGTI TLKLYRVLKV FLSRSAQRMP YMSSGRVLRM LGLILLLVLW
FLAAWTVGML ENIDKNIPLV IRSRTATGLQ FYICDHDRWD YMMVVAEMLF LLWGSFLCYA
TRTVPSAFHE PRYMGIALHN EMIISAAFHV VRFVMVPSLH PDWTLLLFFV HTHGTITLTL
ALLFVPKFLQ AGAPLREEIA AEVYEDELDM RRSGSYLNNS IASAWSEHSL DPDDIRDELK
KLYTQLEVHK TKKMTANNPH LQKKRSSKRG LGRSIMRRLT EIPESVSRQC SKDSSSSSVK
VKEDASKHKA FSLRKSHSTY DHMREPKEPP LLDSLMRKKL AKKASERANS ESLDSAPLVY
KSASAHNLLA DKKPLHPKPS PLQKSLSVLM SAREKALLLT SRAYLEDSCQ APGENEREDS
SDRAAVCPWE GDATPQDKAQ KHVTYAPIKS ISVDSSQLAG RAPLAGKRTP PQPPVRYQSL
AHSLERSEQT RPATDMPRQG SKDNTARINI CPWEVEELPG TTEEAEWGDE NVQPPSAAGH
GRLLPAPSFA AEICPWELAE EEVLKPSQQE KPSEPGGTEK PPGSLAKPLS LQTPPQKSSI
RSIGLAMKAF HRVREKGSVT RKEDEASQRK KDKDAGSQSR GPEESRPKII SKQATICPWE
EETTSPAQQN NTTSKVLEIC PWEEAGSAVE KKGSKGTGNT IRRKLERMRS QWESMCPWEN
TETEAPSAEA DAKPASPPKG AAKKADSVES RRAEVCPWQT EEADANVNAE AGSWEVAETP
PGKRMRQGLS QEAKSSALKA ATGPSKTADT VNRQREATCP WESVDTEEAA VKADRKSFDL
TKKSGSVESK RVAVCPWESE EGEASVSPAV CPWDVSPAPS DKGKLKQERD AVSKGAASLS
PKATASASKF LEKGSCPREA ICPWESMDME EALGETNRKS CDLSISPSRK SGSVESKKAE
VCPWETEEVE TSVRPEICPW EAADAPSEKG TLLRKAGVAS TKEQSKKGAQ DKVGDHGVAL
KAAAGSSKQL EKGRSQTEAI CPREGRSMEE SSVKADRKSF ELSKGPSKES KKAEVCPWES
EEVEASIKAE ICPWEVLEAP SDKGKLRQDA GESDKKGLRG MGDIPAKKLE KESSQRESVC
PWEDFSVTDT GNISSRKSDS VESKKSDICP WEGLDPRAVE KADICPWEVE GAPAGDRETS
QTSEGCPLEA GAVSLVCATP AKSKPAETRE EEAGGPSPTK SDICPW
//
