ID K7FK70_PELSI Unreviewed; 185 AA.
AC K7FK70;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000008430.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000008430.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AGCU01137462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01137463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01137464; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01137465; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01137466; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01137467; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01137468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01137469; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01137470; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01137471; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FK70; -.
DR Ensembl; ENSPSIT00000008474.1; ENSPSIP00000008430.1; ENSPSIG00000007692.1.
DR GeneTree; ENSGT00940000163741; -.
DR HOGENOM; CLU_004826_3_4_1; -.
DR OMA; PGFERIC; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 3.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR PANTHER; PTHR12916; CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2; 1.
DR PANTHER; PTHR12916:SF4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED; 1.
DR Pfam; PF00008; EGF; 3.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS00022; EGF_1; 4.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 7..43
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 45..81
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 83..119
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 121..157
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 11..21
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 33..42
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 71..80
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 109..118
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 147..156
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 185 AA; 20168 MW; E0C508273345E81A CRC64;
GKNCSEIIGQ CQPHVCLNGN CSNVTPNTFL CKCNKDFTGP FCEEPVEHCI SQPCLNGGIC
QNNEHGYVCE CLAGYFGHDC EADVNECSSR PCQNGATCID MSNDVTCICL PMFTGKFCDN
VLRPCELSPC LNNATCVDQQ HSYYCCCMPG FTGKNCEEVI DYCRLLSINC LNEGLCLNII
GGFSV
//
