ID K7FTR2_PELSI Unreviewed; 552 AA.
AC K7FTR2;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Neuralized E3 ubiquitin protein ligase 1B {ECO:0000313|Ensembl:ENSPSIP00000011422.1};
GN Name=NEURL1B {ECO:0000313|Ensembl:ENSPSIP00000011422.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000011422.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000011422.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01196064; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01196065; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01196066; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01196067; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01196068; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01196069; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01196070; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006138195.1; XM_006138133.2.
DR AlphaFoldDB; K7FTR2; -.
DR Ensembl; ENSPSIT00000011479.1; ENSPSIP00000011422.1; ENSPSIG00000010315.1.
DR GeneID; 102457424; -.
DR CTD; 54492; -.
DR GeneTree; ENSGT00940000157079; -.
DR OrthoDB; 5471056at2759; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16786; mRING-HC-C3HC5_NEU1B; 1.
DR Gene3D; 2.60.120.920; -; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR037962; Neuralized.
DR InterPro; IPR006573; NHR_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12429:SF10; E3 UBIQUITIN-PROTEIN LIGASE NEURL1B; 1.
DR PANTHER; PTHR12429; NEURALIZED; 1.
DR Pfam; PF07177; Neuralized; 2.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00588; NEUZ; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51065; NHR; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 39..195
FT /note="NHR"
FT /evidence="ECO:0000259|PROSITE:PS51065"
FT DOMAIN 277..431
FT /note="NHR"
FT /evidence="ECO:0000259|PROSITE:PS51065"
FT DOMAIN 500..540
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 552 AA; 61486 MW; EFDDD6E1DCBF81DE CRC64;
MILKWWYTSH QTRSVSSRPH YPLPNSSQER RSVLAIAEPP RFHSQAKGKN VHLDAHSRKA
TRRNSFCNGV TFTHRPIHLY EKVRLKLVSV HHGWSGALRF GFTTHDPSHM SSDDIPKYAC
PDLVTRPGYW AKALPERFAL RDNILAFWVD RHGRVFYSIN DEEPVLFHCG VKVPGPLWAL
IDVYGITHEV QILDSMFAET MTSTHFSSAR LSSCLPQSSH DSANFNNNEL ENNQVVAKIA
NLNLSRVPGL SVDNHIIPCC PNRRQRTPGV PAFLDTDLHF HLTRGPDITF SQDRMVACTN
WQESNRTLMF SDRPLHIGES LFVEIGHLGL PYHGALSFGI TSCDPGTLRT NELPADPDYL
LDRKEYWVVY RAFPALSNGD ILTFVVLPSG EVHHGMNGVS RGMLMCVDTS QSLWVFFTIH
GVINQLKILG TVQSSPGTVS PSGSPGGSQY DSDSDMAFSV NRSSSASESS LVTAPSSPLS
PPVSPVFPPP EPLCSKNGEC TVCFDSEVDT VIYTCGHMCL CNTCGLRLKK QLNACCPICR
RVIKDVIKIY RP
//
