ID K7FWY3_PELSI Unreviewed; 1222 AA.
AC K7FWY3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Sorbin and SH3 domain containing 2 {ECO:0000313|Ensembl:ENSPSIP00000012543.1};
GN Name=SORBS2 {ECO:0000313|Ensembl:ENSPSIP00000012543.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000012543.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000012543.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01122666; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01122667; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01122668; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01122669; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01122670; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01122671; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01122672; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01122673; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01122674; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01122675; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7FWY3; -.
DR STRING; 13735.ENSPSIP00000012543; -.
DR Ensembl; ENSPSIT00000012604.1; ENSPSIP00000012543.1; ENSPSIG00000011028.1.
DR eggNOG; KOG4225; Eukaryota.
DR GeneTree; ENSGT00940000157056; -.
DR HOGENOM; CLU_003951_1_0_1; -.
DR OMA; WYEGEHL; -.
DR TreeFam; TF320680; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR CDD; cd11923; SH3_Sorbs2_2; 1.
DR CDD; cd11917; SH3_Sorbs2_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003127; SoHo_dom.
DR PANTHER; PTHR14167:SF56; DREBRIN-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR Pfam; PF00018; SH3_1; 2.
DR Pfam; PF14604; SH3_9; 1.
DR Pfam; PF02208; Sorb; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 3.
DR SMART; SM00459; Sorb; 1.
DR SUPFAM; SSF50044; SH3-domain; 3.
DR PROSITE; PS50002; SH3; 3.
DR PROSITE; PS50831; SOHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 168..229
FT /note="SoHo"
FT /evidence="ECO:0000259|PROSITE:PS50831"
FT DOMAIN 984..1043
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1059..1120
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1163..1222
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 27..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 231..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..814
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1123..1151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..263
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..283
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..334
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..811
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1136..1151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1222 AA; 137214 MW; 228EC4FB2CBD5642 CRC64;
MNTDSGGCAR KRAAMSVMLT AVKRVQSSPN LLAPGPDSQS PDSAWASYND GSRETLNGDT
SSSSLAAKGF RSVRPNLQEK KSPTQAQITV NGNSGTVTSP MSHFQRPFSP SSAYSPPASL
NSNIIMQHGR KMDSTETYSQ YAQSFGSSTA PSTIPICRSS EEEKKVTVIR APHYAGIGPV
DESGIPTAIR TTVDRPKDWY KTMFKQIHMV HKPDDVTDMY NAAYAYNTGS YSPSPSAQPH
PAAKTQTYRP LPKSISDNGT DAFKVSSPIP PPHVPPPIPP LRPRERSTPE KNDWDPPDRK
VDTRKFRSEP RSIFEYEPGK SSILEHERPP PKKLLDYVQD NSPGVSNETS LYHPSDKGLD
RPSSRAISSS DYRKRRKSEP AVSHQRVHSD QNANRTSGGH ADMQGTYTTL RKPLTNSSPS
SPSRAKGGDI SKVYPSLFSY SLHNHNTSNE LDYCSTYSQH LAVPSDSRRA IHYKNGWQMT
RQNAEVWSST EETASPKRKS RSCDDLLTDD HDSFPDAQAK SESMVSLICE EDSKGSCSLT
WASPYVPESR GASRSRVRHR SAHDAPGFLK MYKKMHRINR KDLMNSEVIC SVKSRILQYE
KEQHKGMLQG WRESSTEEVP RDMVPTRISE FEKLIQKSKS MPNLGDETLS TVSLELPKNG
LCPQRRFSIE SLLEEENQGR HGIQVQRNCK SKTLVPIQIE VTSDEPQRSH LEFSDSDQDG
VVSDLSDFIQ IEGSSFCSES DFDHFSFTSS ESFYGSGHHH HHHHHHHHHH KHLISSCKGR
CPASYTRFTT MLKHERAKQD STEDPRRQES ESGLSKIAFL VSPVPFRRKK SSAPKKQTEK
TKCKSSMVEA LDSALKDICD QIKAEKRRGS LPDNSILHRL ITELLPDIPE RNSSLKALRK
SPMHQPFHPL PQDGAIHCPL YQNDCGRLPL SASFQDMDTT NNNNPNNDSA LSFQVDQESR
GNYSSALTDV GRCTPRERRG IPDRERLPAR AVYDFKAQTS KELSFKKGDT IYILRKIDQN
WYEGEHHARV GIFPISYVEK LCPPEKAQPA RPPPPAQIGD IGEAIAKYNF NADTNVELSL
RKGDRVILLK RVDQNWYEGK IPGSNRQGIF PVSYVEVIKK NASKGAGDYP DPPIPQSYSS
DRTHHLSSTK PQRPVFAHEN IHSGGEPFQA LYNYTPRNED ELELREGDII DVMEKCDDGW
FVGTSRRTKF FGTFPGNYVK RL
//
