ID K7FZZ8_PELSI Unreviewed; 334 AA.
AC K7FZZ8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Zinc finger Ran-binding domain-containing protein 2 {ECO:0000256|ARBA:ARBA00017543, ECO:0000256|PIRNR:PIRNR037956};
GN Name=ZRANB2 {ECO:0000313|Ensembl:ENSPSIP00000013608.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000013608.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000013608.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May interfere with constitutive 5'-splice site selection.
CC {ECO:0000256|PIRNR:PIRNR037956}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR037956}.
CC -!- SIMILARITY: Belongs to the ZRANB2 family.
CC {ECO:0000256|ARBA:ARBA00025731, ECO:0000256|PIRNR:PIRNR037956}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGCU01072062; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01072063; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006121124.1; XM_006121062.1.
DR AlphaFoldDB; K7FZZ8; -.
DR STRING; 13735.ENSPSIP00000013608; -.
DR Ensembl; ENSPSIT00000013672.1; ENSPSIP00000013608.1; ENSPSIG00000012222.1.
DR GeneID; 102450007; -.
DR KEGG; pss:102450007; -.
DR CTD; 9406; -.
DR eggNOG; KOG1995; Eukaryota.
DR GeneTree; ENSGT00730000111078; -.
DR HOGENOM; CLU_061048_0_0_1; -.
DR OMA; DLWGDNE; -.
DR OrthoDB; 585295at2759; -.
DR TreeFam; TF105996; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 2.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR InterPro; IPR017337; ZRANB2.
DR PANTHER; PTHR12999:SF17; ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR12999; ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED; 1.
DR Pfam; PF00641; zf-RanBP; 2.
DR PIRSF; PIRSF037956; UCP037956_ZnF_Ran; 1.
DR SMART; SM00547; ZnF_RBZ; 2.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 2.
DR PROSITE; PS01358; ZF_RANBP2_1; 2.
DR PROSITE; PS50199; ZF_RANBP2_2; 2.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRNR:PIRNR037956}; Nucleus {ECO:0000256|PIRNR:PIRNR037956};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PIRNR:PIRNR037956};
KW Zinc {ECO:0000256|PIRNR:PIRNR037956};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 9..40
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 65..94
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT REGION 117..334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..132
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..181
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..312
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 334 AA; 37722 MW; BBD0CE9C5DDA8F6A CRC64;
MSTKNFRVSD GDWICPDKKC GNVNFARRTS CNRCGREKTT EAKMMKAGGT EIGKTLAEKS
RGLFSANDWQ CKTCGNVNWA RRSECNMCNT PKYAKLEERT GYGGGFNERE NVEYIEREES
DGEYDEFGRK KKKYRGKPVG PASILKEVED KESEGEEEED EDEDLSKYKL DEDEDEEDAD
LSKYNLDASE EEDANKKKKP NRRSRSKSRS SHSQSSSRSS SHSSSRSRSR SRSRSSSSSR
SRSRSTSREH SRSRGSKSRS SSRSVRGSSS PRKRSYSSSR SSSSPERGKK RSRSRSSSSG
DRKKRRSRSR SPERHRGSSS GSSHSGSRTS SKKK
//
