ID K7G567_PELSI Unreviewed; 700 AA.
AC K7G567;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=G2/M-phase specific E3 ubiquitin protein ligase {ECO:0000313|Ensembl:ENSPSIP00000015428.1};
GN Name=G2E3 {ECO:0000313|Ensembl:ENSPSIP00000015428.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000015428.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000015428.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01041646; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01041647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7G567; -.
DR STRING; 13735.ENSPSIP00000015428; -.
DR Ensembl; ENSPSIT00000015500.1; ENSPSIP00000015428.1; ENSPSIG00000013682.1.
DR eggNOG; KOG1084; Eukaryota.
DR GeneTree; ENSGT00950000182865; -.
DR OMA; FRNQKFN; -.
DR TreeFam; TF325426; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd15669; ePHD_PHF7_G2E3_like; 1.
DR CDD; cd15496; PHD_PHF7_G2E3_like; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR042013; PHF7/G2E3_ePHD.
DR InterPro; IPR042012; PHF7/G2E3_PHD.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12420:SF37; G2_M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE; 1.
DR PANTHER; PTHR12420; PHD FINGER PROTEIN; 1.
DR Pfam; PF00632; HECT; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00119; HECTc; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1..82
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
SQ SEQUENCE 700 AA; 79536 MW; 673DB17E178B3708 CRC64;
MSSGIWQRGE EDEGVHGFLI NDIRKEVTRA AKLTCNICKK KGASIGCVAP KCKRSYHFPC
GVQRECIFQF MENFGSYCWE HRPVQKLPSG ESRGSSQCTI CLEFVERIPL YNVLKSPCCK
NAWFHRDCLQ YQALSAGIFF FRCTVCNNKD KFQNEMLRMG IHIPEKDASW ELEENAYQDL
LQRYQHCDAR TCLCKNGRDY SKPDSKWEIK RCQCCGSCGT HLACSPMQSW EENWECMECR
SIFAKSGYYQ NQKKRSLTNS EKIDVTGRLL EEPSPKCPRQ SPGSQHSFHL RSTKMLCQNS
LTPCTLLDLP ASNKMAMSIS PLINSSSRSL SVRRMQLRIQ KREASNILRE LKSQINTKTT
RLNINRDDIW SSALKGFRGR NFNPANTMEI KFTNCKDKTE TYTFHGSKHE FFQLLMLHLK
ISSLFEGSSS KNLSLDSQAI KENLYYEAGK MIAVSLVHGG PPPGFFSKTL FNCLAYGPEN
VKPTEEDVAD SDVAQTINMI KSSRTLAHLQ STISDCYEYL TVTGCLRPMT TLSDKDMLVN
DILIYHVIKR VLSPFESFRQ GLKTLGVLEK LQSHPDAFSS ILCHKPERLS AKILGDLFTI
HCVSNLNREK GVDFWMGYLQ DVEGGESAAT LEDILVFATG TSSIPPIGFE PEPSVEFMYI
KYPVGNRQPN CLQLPITKTY EQFKNKMDFA ISSTLRLTGV
//
