ID K7G8N7_PELSI Unreviewed; 353 AA.
AC K7G8N7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Septin 12 {ECO:0000313|Ensembl:ENSPSIP00000016648.1};
GN Name=SEPTIN12 {ECO:0000313|Ensembl:ENSPSIP00000016648.1};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000016648.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000016648.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|RuleBase:RU004560}.
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DR EMBL; AGCU01096382; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01096383; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01096384; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01096385; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01096386; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01096387; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01096388; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01096389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7G8N7; -.
DR STRING; 13735.ENSPSIP00000016648; -.
DR Ensembl; ENSPSIT00000016724.1; ENSPSIP00000016648.1; ENSPSIG00000014795.1.
DR eggNOG; KOG1547; Eukaryota.
DR GeneTree; ENSGT00940000158310; -.
DR HOGENOM; CLU_017718_7_1_1; -.
DR OMA; AHCEFLL; -.
DR TreeFam; TF101078; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0031105; C:septin complex; IEA:Ensembl.
DR GO; GO:0097227; C:sperm annulus; IEA:Ensembl.
DR GO; GO:0005819; C:spindle; IEA:Ensembl.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF66; SEPTIN-12; 1.
DR Pfam; PF00735; Septin; 1.
DR PIRSF; PIRSF006698; Septin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 46..320
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 324..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 353 AA; 38474 MW; 885F83DA50944257 CRC64;
MEGQPGQPAP EETPRGANPA SGGLELFGYV GIEAVLDQMR IKTMKTGFEF NLMVVGQSGL
GKSTMVNTLF KSKVSRKPAG PGYEERIPKT VQLQTGSHVI EEKGVRMKLT VTDTPGFGDQ
INNENCWDPI IKYISEQYEK YLREEILISR QRKIPDTRVH GCVYFVPPTG HWLRPLDLEF
MQRLSKIVNV VPVIAKADTL TLEERAEFKQ RIQKDLKAHG IRAAPPAPVF TSPARAHSAS
APFHDSPCFQ AGAGAGRGGC SEGLFSPASA TPVSCFAVEN PAHCEFPLLR DLLIRSHLQD
LKDITHNVHY ARATSRRWGT CQVLPQGPHG SPASPAPGPL GTELAGPMSP APL
//
