ID K7GHB6_PELSI Unreviewed; 446 AA.
AC K7GHB6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Alpha-2-macroglobulin bait region domain-containing protein {ECO:0000259|SMART:SM01359};
OS Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia;
OC Trionychidae; Pelodiscus.
OX NCBI_TaxID=13735 {ECO:0000313|Ensembl:ENSPSIP00000019677.1, ECO:0000313|Proteomes:UP000007267};
RN [1] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RG Soft-shell Turtle Genome Consortium;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000007267}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Daiwa-1 {ECO:0000313|Proteomes:UP000007267};
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
RN [3] {ECO:0000313|Ensembl:ENSPSIP00000019677.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGCU01064303; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AGCU01064304; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; K7GHB6; -.
DR STRING; 13735.ENSPSIP00000019677; -.
DR Ensembl; ENSPSIT00000019769.1; ENSPSIP00000019677.1; ENSPSIG00000017459.1.
DR eggNOG; KOG1366; Eukaryota.
DR GeneTree; ENSGT00940000154904; -.
DR HOGENOM; CLU_001634_2_1_1; -.
DR OMA; IVAFHEF; -.
DR Proteomes; UP000007267; Unassembled WGS sequence.
DR Gene3D; 2.20.130.20; -; 1.
DR Gene3D; 2.60.40.1930; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR011625; A2M_N_BRD.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041555; MG3.
DR InterPro; IPR040839; MG4.
DR PANTHER; PTHR11412:SF165; ALPHA-2-MACROGLOBULIN; 1.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR Pfam; PF07703; A2M_BRD; 1.
DR Pfam; PF17791; MG3; 1.
DR Pfam; PF17789; MG4; 1.
DR SMART; SM01359; A2M_N_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007267}.
FT DOMAIN 222..370
FT /note="Alpha-2-macroglobulin bait region"
FT /evidence="ECO:0000259|SMART:SM01359"
SQ SEQUENCE 446 AA; 48730 MW; 07A6B70210FE34CB CRC64;
MPKKITIQDE ELKVAVCGLY TYGPPVPGLV NVRVCRRFSQ ARSDCYGREG EAVCEEFTGK
ADSQGCVSSV VKTKIFQLKR NGYEMKIEVE GKITEEGTGV ELTGTDSSEI TGTMSKISFE
QVDSHYRPGI PFFGQVKLVD GTDAPIANER IQISMGGNKY ATNKTGQVWF SIDTVNFTDT
SIQIAATHKS ELNCYDSTWV TPEYGSAHHS VTRFYSPSQS FLKIEPVPQT FSCGSSVGVR
VHYILKPEAV QEQKEIVFYY LVMAKGGIVS AGTEEHPVGD GELVQVFELR VPVGPEIAPL
ARVLVYTTLP SGEVVANSED FKIENCFANK VDLHFSPVEG LPASDAHLQV RASPGSLCAV
RAVDKSVLLM KPEAELSPSS VYDLLPVKDI RGYDYRGHHV EEEDENPCVS LSNVILNGFI
YTPVSPDGEG DAFHILKVSA RPPGSV
//
