ID K7REK6_9EUKA Unreviewed; 467 AA.
AC K7REK6;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=FeFe-hydrogenase 5 {ECO:0000313|EMBL:AFV80060.1};
DE SubName: Full=[FeFe]-hydrogenase 5 {ECO:0000313|EMBL:EST43080.1};
GN ORFNames=SS50377_17238 {ECO:0000313|EMBL:AFV80060.1}, SS50377_25027
GN {ECO:0000313|EMBL:KAH0572912.1};
OS Spironucleus salmonicida.
OG Hydrogenosome {ECO:0000313|EMBL:AFV80060.1}.
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Hexamitinae;
OC Spironucleus.
OX NCBI_TaxID=348837 {ECO:0000313|EMBL:AFV80060.1};
RN [1] {ECO:0000313|EMBL:AFV80060.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 50377 {ECO:0000313|EMBL:AFV80060.1};
RA Jerlstrom-Hultqvist J., Einarsson E., Xu F., Hjort K., Ek B., Steinhauf D.,
RA Hultenby K., Bergquist J., Andersson J.O., Svard S.G.;
RT "Hydrogenosomes in the diplomonad Spironucleus salmonicida.";
RL Nat. Commun. 2493:42493-42493(2013).
RN [2] {ECO:0000313|EMBL:KAH0572912.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 50377 {ECO:0000313|EMBL:KAH0572912.1};
RX PubMed=24516394;
RA Xu F., Jerlstrom-Hultqvist J., Einarsson E., Astvaldsson A., Svard S.G.,
RA Andersson J.O.;
RT "The Genome of Spironucleus salmonicida Highlights a Fish Pathogen Adapted
RT to Fluctuating Environments.";
RL PLoS Genet. 10:E1004053-E1004053(2014).
RN [3] {ECO:0000313|EMBL:EST43080.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu F., Jerlstrom-Hultqvist J., Einarsson E., Astvaldsson A., Svard S.G.,
RA Andersson J.O.;
RT "The Genome of Spironucleus salmonicida Highlights a Fish Pathogen Adapted
RT to Fluctuating Environments.";
RL PLoS Genet. 0:0-0(2014).
RN [4] {ECO:0000313|EMBL:KAH0572912.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 50377 {ECO:0000313|EMBL:KAH0572912.1};
RA Xu F., Kurt Z., Jimenez-Gonzalez A., Astvaldsson A., Andersson J.O.,
RA Svard S.G.;
RT "New Spironucleus salmonicida genome in near-complete chromosomes.";
RL Submitted (DEC-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NARF family.
CC {ECO:0000256|ARBA:ARBA00006596}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JX549085; AFV80060.1; -; Genomic_DNA.
DR EMBL; KI546146; EST43080.1; -; Genomic_DNA.
DR EMBL; AUWU02000005; KAH0572912.1; -; Genomic_DNA.
DR EnsemblProtists; EST43080; EST43080; SS50377_17238.
DR VEuPathDB; GiardiaDB:SS50377_25027; -.
DR OrthoDB; 5477067at2759; -.
DR Proteomes; UP000018208; Unassembled WGS sequence.
DR GO; GO:0042566; C:hydrogenosome; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.1780; -; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR PANTHER; PTHR11615:SF6; NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR Pfam; PF13187; Fer4_9; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW Hydrogenosome {ECO:0000313|EMBL:AFV80060.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018208}.
FT DOMAIN 21..51
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 71..100
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 467 AA; 51029 MW; 50710277AD0D698D CRC64;
MKVRQSPFKI DITNGPIDRN DAIQIDYQKC IGCQMCAKTC TDSQNFNIFK ISAPKTKPFV
NAYGSVAEGT ERNALAGTDC TGCGACVRAC PVEALMPAFN IRPVLEQISE KKKVTIAVIA
PSTRVGLAEG MGMGVGVTAE RQMVYELKQM GFDYVFDNMW GADATTTEDA KEILKAKAAG
KTAFTSCCPA WVKLVETTYP ELLPNISSAR SPHGIICSVI KKYFAKDIGK KADELYVVGV
MPCTAKKNEA ARKELTTDGS PDCDISITTR ELMAYLKEKK VTFSAAREIE LKDNVQAQYD
APFNTFSGSA YIYGKTAGVT EAVVRYVCAI KKVPFSVGMI TKELIWENKL HSSSLTLLTF
SAAGEDYRIC VSYGGLAAHK AVELYKSGEL KVDAVEVMVC PGGCVGGGGQ PKQPKKDMIL
KRHEGLDKHD KEAPYSNCTE NPTLNEFYER IGTDVHHVMH TTYSAYK
//
