ID   K7ZWN8_YERPU            Unreviewed;       986 AA.
AC   K7ZWN8;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   SubName: Full=Invasin {ECO:0000313|EMBL:CCH50679.1};
GN   Name=inv {ECO:0000313|EMBL:CCH50679.1};
OS   Yersinia pseudotuberculosis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=633 {ECO:0000313|EMBL:CCH50679.1};
RN   [1] {ECO:0000313|EMBL:CCH50679.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=43K.3 {ECO:0000313|EMBL:CCH50687.1}, P30
RC   {ECO:0000313|EMBL:CCH50684.1}, T3.2.2K {ECO:0000313|EMBL:CCH50689.1},
RC   T6.2.2C {ECO:0000313|EMBL:CCH50692.1}, and WS899K
RC   {ECO:0000313|EMBL:CCH50679.1};
RA   Palonen E., Kangas S., Somervuo P., Lindstrom M., Fredriksson-Ahomaa M.,
RA   Skurnik M., Korkeala H.;
RT   "Sequencing of Virulence Genes Shows Limited Genetic Variability in
RT   Yersinia pseudotuberculosis.";
RL   Foodborne Pathog. Dis. 0:0-0(2012).
CC   -!- SIMILARITY: Belongs to the intimin/invasin family.
CC       {ECO:0000256|ARBA:ARBA00010116}.
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DR   EMBL; HE805214; CCH50679.1; -; Genomic_DNA.
DR   EMBL; HE805219; CCH50684.1; -; Genomic_DNA.
DR   EMBL; HE805222; CCH50687.1; -; Genomic_DNA.
DR   EMBL; HE805224; CCH50689.1; -; Genomic_DNA.
DR   EMBL; HE805227; CCH50692.1; -; Genomic_DNA.
DR   AlphaFoldDB; K7ZWN8; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1080; -; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   Gene3D; 2.40.160.160; Inverse autotransporter, beta-domain; 1.
DR   Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR   InterPro; IPR003344; Big_1_dom.
DR   InterPro; IPR016186; C-type_lectin-like/link_sf.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR024519; IAT_beta.
DR   InterPro; IPR038177; IAT_beta_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003535; Intimin/invasin_bac.
DR   InterPro; IPR013117; Intimin_C.
DR   InterPro; IPR008964; Invasin/intimin_cell_adhesion.
DR   InterPro; IPR048658; Invasin_D4.
DR   InterPro; IPR015217; Invasin_dom_3.
DR   PANTHER; PTHR39576:SF2; ATTACHING AND EFFACING PROTEIN HOMOLOG-RELATED; 1.
DR   PANTHER; PTHR39576; ATTACHING AND EFFACING PROTEIN HOMOLOG-RELATED-RELATED; 1.
DR   Pfam; PF02369; Big_1; 1.
DR   Pfam; PF11924; IAT_beta; 1.
DR   Pfam; PF07979; Intimin_C; 1.
DR   Pfam; PF09134; Invasin_D3; 2.
DR   Pfam; PF21764; Invasin_D4; 1.
DR   PRINTS; PR01369; INTIMIN.
DR   SMART; SM00634; BID_1; 3.
DR   SUPFAM; SSF56436; C-type lectin-like; 1.
DR   SUPFAM; SSF49373; Invasin/intimin cell-adhesion fragments; 4.
DR   PROSITE; PS51127; BIG1; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          504..597
FT                   /note="Big-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51127"
FT   DOMAIN          602..692
FT                   /note="Big-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51127"
SQ   SEQUENCE   986 AA;  106675 MW;  A7BB3EBF4634F1FD CRC64;
     MMVFQPISEF LLIRNAGMSM YFNKIISFNI ISRIVICIFL ICGMFMAGAS EKYDANAPQQ
     VQPYSVSSSA FENLHPNNEM ESSINPFSAS DTERNAAIID RANKEQETEA VNKMISTGAR
     LAASGRASDV AHSMVGDAVN QEIKQWLNRF GTAQVNLNFD KNFSLKESSL DWLAPWYDSA
     SFLFFSQLGI RNKDSRNTLN LGVGIRTLEN GWLYGLNTFY DNDLTGHNHR IGLGAEAWTD
     YLQLAANGYF RLNGWHSSRD FSDYKERPAT GGDLRANAYL PALPQLGGKL MYEQYTGERV
     ALFGKDNLQR NPYAVTAGIN YTPVPLLTVG VDQRMGKSSK HETQWNLQMN YRLGESFQSQ
     LSPSAVAGTR LLAESRYNLV DRNNNIVLEY QKQQVVKLTL SPATISGLPG QVYQVNAQVQ
     GASAVREIVW SDAELIAAGG TLTPLSTTQF NLVLPPYKRT AQVSRVTDDL TANFYSLSAL
     AVDHQGNRSN SFTLSVTVQQ PQLTLTAAVI GDGAPANGKT AITVEFTVAD FEGKPLAGQE
     VVITTNNGAL PNKITEKTDA NGVARIALTN TTDGVTVVTA EVEGQRQSVD THFVKGTIAA
     DKSTLAAVPT SIIADGLMAS TITLELKDTY GDPQAGANVA FDTTLGNMGV ITDHNDGTYS
     APLTSTTLGV ATVTVKVDGA AFSVPSVTVN FTADPIPDAG RSSFTVSTPD ILADGTMSST
     LSFVPVDKNG HFISGMQGLS FTQNGVPVSI SPITEQPDSY TATVVGNTAG DVTITPQVDT
     LILSTLQKKI SLFPVPTLTG ILVNGQNFAT DKGFPKTIFK NATFQLQMDN DVANNTQYEW
     SSSFTPNVSV NDQGQVTITY QTYSEVAVTA KSKKFPSYSV SYRFYPNRWI YDGGTSLVSS
     LEASRQCQGS DMSAVLESSR ATNGTRAPDG TLWGEWGSLT AYSSDWQSGE YWVKKTSTDF
     ETMNMDTGAL VQGPAYLAFP LCALAI
//