ID K8DZ22_9FIRM Unreviewed; 383 AA.
AC K8DZ22;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Histidine kinase HAMP region domain protein {ECO:0000313|EMBL:CCO08209.1};
GN ORFNames=DESHY_20078 {ECO:0000313|EMBL:CCO08209.1};
OS Desulforamulus hydrothermalis Lam5 = DSM 18033.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae;
OC Desulforamulus.
OX NCBI_TaxID=1121428 {ECO:0000313|EMBL:CCO08209.1, ECO:0000313|Proteomes:UP000009315};
RN [1] {ECO:0000313|EMBL:CCO08209.1, ECO:0000313|Proteomes:UP000009315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lam5 / DSM 18033 {ECO:0000313|Proteomes:UP000009315};
RX PubMed=23405336; DOI=10.1128/genomeA.00114-12;
RA Amin O., Fardeau M.L., Valette O., Hirschler-Rea A., Barbe V., Medigue C.,
RA Vacherie B., Ollivier B., Bertin P.N., Dolla A.;
RT "Genome Sequence of the Sulfate-Reducing Bacterium Desulfotomaculum
RT hydrothermale Lam5(T).";
RL Genome Announc. 1:e00114-e00112(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCO08209.1}.
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DR EMBL; CAOS01000009; CCO08209.1; -; Genomic_DNA.
DR RefSeq; WP_008411502.1; NZ_FQXF01000016.1.
DR AlphaFoldDB; K8DZ22; -.
DR STRING; 1121428.DESHY_20078; -.
DR eggNOG; COG4565; Bacteria.
DR OrthoDB; 9814363at2; -.
DR Proteomes; UP000009315; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45526:SF5; TRANSCRIPTIONAL REGULATORY PROTEIN DCUR; 1.
DR PANTHER; PTHR45526; TRANSCRIPTIONAL REGULATORY PROTEIN DPIA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF08279; HTH_11; 1.
DR Pfam; PF17202; sCache_3_3; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CCO08209.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009315};
KW Transferase {ECO:0000313|EMBL:CCO08209.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 205..257
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 383 AA; 42433 MW; AAC40EEC4D9AA01B CRC64;
MQSLKQQITI LVVVVTLVLA VCFMIAVGLQ IKKSSELAAI TKAKSDIATA KTIIDLKYPG
PWHVVDGYLY KGEVKMNNNF EVVDYISSLT GDTCTLFLGN TRVATTIKKA DGQRAVGTHS
SDVVAKKVLT EGKDYLGEAE VVGEKYQTAY SPIYDHRGNI IGMFYVGISK KFYDQLLYES
LWRMALIGTA LTLLVFGGTL YFTQKFIIEP LKLIQAETQK VAAGNISASV AIGYKNEIGE
LAHSFNQLVE LIQGLTQQIS KNAGAVLPPA NHAVIADGVI ADTENHEATV CEQLKEVKEI
KEDWGELPKG LNETTLQQIL NYLKSRQGHL SVSEIAEEVK LTKVTVRRYL DFMEKCGRVK
VEMQYGPIGR PLKLYTLLSN YRQ
//
