ID   K8E2I1_CARML            Unreviewed;       446 AA.
AC   K8E2I1;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 2.
DT   24-JAN-2024, entry version 46.
DE   RecName: Full=Permease IIC component {ECO:0000256|PIRNR:PIRNR006351};
GN   ORFNames=BN424_716 {ECO:0000313|EMBL:CCO10180.2};
OS   Carnobacterium maltaromaticum LMA28.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC   Carnobacterium.
OX   NCBI_TaxID=1234679 {ECO:0000313|EMBL:CCO10180.2, ECO:0000313|Proteomes:UP000000212};
RN   [1] {ECO:0000313|Proteomes:UP000000212}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=LMA28 {ECO:0000313|Proteomes:UP000000212};
RX   PubMed=23405327; DOI=10.1128/genomeA.00115-12;
RA   Cailliez-Grimal C., Chaillou S., Anba-Mondoloni J., Loux V., Afzal M.I.,
RA   Rahman A., Kergourlay G., Champomier-Verges M.C., Zagorec M., Dalgaard P.,
RA   Leisner J.J., Prevost H., Revol-Junelles A.M., Borges F.;
RT   "Complete Chromosome Sequence of Carnobacterium maltaromaticum LMA 28.";
RL   Genome Announc. 1:0-0(2013).
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane.
CC       {ECO:0000256|PIRNR:PIRNR006351}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; HE999757; CCO10180.2; -; Genomic_DNA.
DR   AlphaFoldDB; K8E2I1; -.
DR   STRING; 1234679.BN424_716; -.
DR   KEGG; cml:BN424_716; -.
DR   eggNOG; COG1455; Bacteria.
DR   HOGENOM; CLU_029688_1_0_9; -.
DR   OrthoDB; 1550290at2; -.
DR   Proteomes; UP000000212; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR004501; PTS_EIIC_3.
DR   InterPro; IPR004796; PTS_IIC_cello.
DR   NCBIfam; TIGR00410; lacE; 1.
DR   PANTHER; PTHR33989; -; 1.
DR   PANTHER; PTHR33989:SF4; PTS SYSTEM N,N'-DIACETYLCHITOBIOSE-SPECIFIC EIIC COMPONENT; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   PIRSF; PIRSF006351; PTS_EIIC-Cellobiose; 1.
DR   PROSITE; PS51105; PTS_EIIC_TYPE_3; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR006351};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR006351};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000212};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597,
KW   ECO:0000256|PIRNR:PIRNR006351}; Transferase {ECO:0000313|EMBL:CCO10180.2};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR006351}.
FT   TRANSMEM        39..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        150..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        235..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        409..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          9..427
FT                   /note="PTS EIIC type-3"
FT                   /evidence="ECO:0000259|PROSITE:PS51105"
SQ   SEQUENCE   446 AA;  48772 MW;  4BDFAEBDED73A70C CRC64;
     MMDKLEIFLN KFLGPIANWM NKSKFFSALS EAFMRTTPVT LGAAVLMIIG NFPIPAWVAF
     VESSGLKVHF DSVIGATLNA ISIFIVFNFA YVYAKKENYN PLSAGLLAVG SFFILMPQQV
     AVPTLETAVT KFPSQGIVTG TTNVEAFQTL YTGGTGLLVA IIVGYIVARL YVFLNKKNLV
     VKMPDSVPPN VAESLSPSLL AGAIFIFFFI IRLLFSFTPF GSVFAFVFGS IQAPLQALTG
     SPITIIIIFT IANMLWFFGI HPNMVYGVVM PMLLANSVAN MNAFREGQPL PFLLATVIAQ
     VCGNGFGGQG STYGLVVAMF TAKSERYKQL LKLAGPPSIF NVNEPLVFGA PLMLNPIFFI
     PMAITPLIMG STAWILVKLL NFTELNPLIS LPWTTPAPIL MGLQGGWKYL IIFAVVFILN
     LIIWFPFFRI ADNRAVDEEK AFAESN
//