ID K8EFY3_9CHLO Unreviewed; 4734 AA.
AC K8EFY3;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Dynein heavy chain {ECO:0000313|EMBL:CCO16889.1};
GN ORFNames=Bathy05g04980 {ECO:0000313|EMBL:CCO16889.1};
OS Bathycoccus prasinos.
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Bathycoccaceae; Bathycoccus.
OX NCBI_TaxID=41875 {ECO:0000313|EMBL:CCO16889.1, ECO:0000313|Proteomes:UP000198341};
RN [1] {ECO:0000313|EMBL:CCO16889.1, ECO:0000313|Proteomes:UP000198341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC 1105 {ECO:0000313|EMBL:CCO16889.1,
RC ECO:0000313|Proteomes:UP000198341};
RA Genoscope - CEA;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|ARBA:ARBA00004230}. Cytoplasm, cytoskeleton, flagellum
CC axoneme {ECO:0000256|ARBA:ARBA00004611}.
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DR EMBL; FO082274; CCO16889.1; -; Genomic_DNA.
DR RefSeq; XP_007513331.1; XM_007513269.1.
DR STRING; 41875.K8EFY3; -.
DR GeneID; 19016001; -.
DR KEGG; bpg:Bathy05g04980; -.
DR eggNOG; KOG3595; Eukaryota.
DR OrthoDB; 166463at2759; -.
DR Proteomes; UP000198341; Chromosome_5.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF343; DYNEIN AXONEMAL HEAVY CHAIN 10; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08385; DHC_N1; 2.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 4.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Flagellum {ECO:0000256|ARBA:ARBA00022846};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198341};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1886..2024
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2170..2321
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2531..2681
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2930..3134
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 87..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4336..4355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4424..4450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1235..1297
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3396..3479
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4336..4353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4434..4450
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4734 AA; 535261 MW; BC01FA2E7749F8D9 CRC64;
MAAERGDGEE QEGDTEKLHR EAPDGAPDLQ PPVEREKKDE EGKKTSGYGN RAAQTNARRL
IDCITEWSDV ISSFIKRDLD ITINDGGNGI HSSGSSRSKS SNEIAQTTMK TTTTGPLREI
ERWKERNVER HTLYEQLTCQ EMKKTEQSLE DSIHSAMIED PEQLSKAHQT LTKFRYLRDN
LEALCAQSKE NVKFLATLEG HFMTISRGSF KRIANCLEPT LEALRLVWII SRYYSNDDRM
GQLMGRIADE LSLRINSEID PKMVLTESRE DDGITKDRAE DHADHLSLLT TSTTANIKHS
PSLHPIIADI QDNSNLTLSE KLRDASLALR SWKTNYLKVR ESIERSNRDT RWEFDRERLF
SRTDHIARVC DDLGEMLSAS LDFQTFLSPK FRAVTLDQVG FDDAVRRVSN MNNRVNRCSF
NAFDPSKAED WADIVQVFNG DRVRIERVVR SFIDQSFKNS TSAKAAFELL HSFRTMFNIP
SIPMNSELLG TARDANGHRE NSSLRTSPVR DVLNKQMRDT TRDILDQFGR EIDQTQHFFH
TQRRNVPLLR NQPSVSGKIA WSRALFVSVR RTMRIFKFTS LGEDIQSAAA LDIENKYLHF
SKTVLDYEKE LVRDWSSTVV DESAASLRSF ILIKDPITEV LGVNGRLPHS SVPLFRPNFH
ENLSVLISEA KSISQLGHEI PSAAKAVVLQ EDVYRSHLNN LKDVCSEYSR VTSGLTFQEF
ALFKEKLIEV EEAFEPGCSK LNWNALGFNT FVHSARCAID SFEKSVLEVR RISKSIKELT
ETISELNFFS PSYTDEAEGD IGVLPELDDV MGTLERTRDE IMERAVGKYK EVSNLLSDIE
FCVIGTRSKK APEMQAFYEF SERSVYRALV RAICSSLRSF RRDFISRRDG ANAAYFRCTI
KLCSQDVVIS PSLEEITTRL NSFVDSMQKI GSKFTRWMHG TCREVLQTQC VDDDEVSDED
YDGYRCISGG LENDNILVTA DTSVHEKEGD TFGITFARDL KSSIVLNKSL VASHRAIERL
SRKIVKYVES WDKFQHAVNT KAREESLQMF TDLSGLEFAP LDESFALFNQ YKSRALADSK
RNLIISCANM DATPLIDGIA QECDIWIKEL SRISAAQDRN YLSEMNSKFQ NVNDVMDAVP
SSLDEMKVFV RLVQDIRIDW ETEINILKIK DRVKLRLRVR PEESLSPSTP SSTTQIDAIC
EDMNAALDTL ANWKACEEKI ERVDVDSRHV RMKYEDQLRN DLNEFESACE ETRNDMLKNG
PASDKSLLDL HAGALKLNEF KTKIVDLSNR REALRDSEKA FQFPPRSVSS LQELRENIEE
YMSCYAVIER FDSKVKVHSR VLWDAIDIEK LRAIAEESKR DCETNITESS KTFELIMSIK
KSIALFEETL DLFCTLKSPA MRPRHWEELA RLAKTSIALT TVSLEDVLKL RLYEHAQHVR
DITNRAEREM KIEDDLIKLS AEWEDAKFDL RPLARESKET REKTLILCSV DDITLSLEDS
SLTLQSMSAS KHAAPFQDTV QSWEYNLAHI SDVLEAWIGT QRKWLYLQSI FCGADDIRAQ
LPREADQFDQ IDLAWREIMR STQENLESKV LESCRVEGRL HHLKELSLQL ESCQKSLSQY
LNTKRDAFPR FFFISDDELL SILGTSDPTL VQEHMLKLFD NCAKLIFGPN DESIIGLMSS
EGESFELSEP VQVLGLPVEV WMRKVESAMR ITLKEICKKG IRRYVNASSR TTWILEELGM
VALVGSQIWW TWEVIDVFRR VKNGQDKMAM KLLSEKLTAQ LADLTKLVRS DLTNLERKKV
NTMIIIDVHA RDIIESFVRD SILDESEFAW ESQLRFKWDK KRDDIVINQC SGEFLYGYEY
MGLNGRLVIT GLTDRCYMTL TTALTYRLGG APAGPAGTGK TETTKDLAKS MALLCVVFNC
GEGLDYKAMG AIFTGLVQCG AWGCFDEFNR IDAEVLSVVS SQIHLIQESL KTNAKRFNFE
GKDIALDSRT GIFITMNPGY AGRTELPDNL KALFRPVQMI VPDLQQICEI MLFSEGFDSA
KELAKKMTVL YKLAKEQLSK QSHYDFGLRA LKSVLIMAGA LKRESPELDE QLVLMRALRD
MNLPKFVFED APLFLGLIND LFPGMDCPRV RYPNLNDAVE KDLENSGYQV LTGPSEQVDK
IIQLYETMLT RHTTMVVGET GGGKSVIIKT LARAQDALGK PTKLILLNPK AQSVSELYGS
LDRDTREWTD GLLSNIFREA NRPLPENRES ESRYIVFDGD VDAVWVENMN SVMDDNKLLT
LPNGERIRLR DHCKLLFEVA NLAHASPATV SRCGMVYVDP KTLGFQPICT SWIKKQGTEL
LQSVLSRIFD KYVGTLVEFC LEGVSDEELP PTSSIERTSS NYVEQLCSLL DSLLPLSSKD
AESHRGISFG ESNITAPDEQ VVEFARKIER MSIFALTWSF GATVIKSDRI KFDTFLRKLT
YDPACSCPLN LPDSGTMYDY GYDRSSDTFF SWESKAENIP LAARSSFSSL LIPTADTVRS
SWLLQTLGNA SNKPILFVGA SGTAKTVTIE KVLAEMTGND SKMSYITMNL SSRTSSLDVQ
RAIEDCIEKR TKDVYGPPLG RKLIVFIDDL NMPKEDLYGT QQPIALLKTM LERDGFYDRG
KELNWKTVKD TRFICAMGHP GGARNTVDAR FASLFNIFEI EAPSEENLKA IYRSILEKLA
SELGVNDDGT PCISSLVCEK ILGATLELYD YVLDAFPPTP SKFHYIFNLR DLSRVFEGMS
QSCADSIASE SAFVRLWRNE VLRVFHDRLV DSIDRNLVKQ KIGSLVIDYF DCDENLLKHA
LSDPVLFADF RTELLVGEET MEGEDTGVPE VQDGCSEGVQ EPNDFSVESA LKTTRAQYKD
VGTYEDVKIT FQKALDSCGR KEGPNKKMNL VFFHDALEHA TRIHRVLRQE RGHMLLIGDG
GFGKQSLAKL AAAAAGCSVF EITLTRGYDE NSFREDLKRL FTRVGVDNEK VLFLFTDNHV
ANESFLEHIN SILTSGAVPA LYPDDEKHVI MRSVRDDALK ENVRDSKEEL WRFFISRARM
NLHIVLCMSP TGDLLRSRCR NFPGLVNDTV IDWFTAWPDE ALLSVATTFL SSIDEIPSDL
RGPIANHVVY THQLVTELSI KYKRELNRSN YVTPKNYLDF IANYSRMLGL NRKRIGELKA
RLEGGSSKLI QAGSEVDAMQ KSLNQAKEVV EGETKACEEL LKVITASTTD VKSKQEAASL
KEIELQKEKE TIGTKKKEAE SDLAKAIPAL EAAALALNSL KKEEITELKS FAKPNIAVQK
VCECVMILKG LPNVSWSGAK AMMTDTNFLK SLIEFDKDAI KDKQAKELKT YTKDSKFTPE
EVTKISSAGG GLLKWVFAMI KYNEVARTVN PKRAAAASAE KLLRTKTKEL AKTKLEVEQL
SEELTSLTEQ FQEKTSNQKR LKESAETMEA RLSAAEKLLK GLESERVRWA KEMNELDESM
KNLVGDCLLT SSFLSYSGAF TFEFRKKFTY DTLYEDVKAR NIPVSPSFRL ENLLTTDVEL
GKWASEGLPT DDLSVQNGIL TTKASRYPLC IDPQMQAVRW IKQREGKNLI GKIKTFSDAD
FLKQLELAVK YGLPFLFENV GKHLDPVIDN VLERRITERN GIKTVQIGDS EVEWDDNFRL
YMTSKLPNPS YGPEVSGKTM IINYGVTLVG LQEQLLNVTV KMERPDLELQ RESLVQETSV
NKSLLKDLED TLLMELSSAS GEILDNVELI TTLDETKYKA KEISCKLEEA KAASEKLVLA
RRAYEPIAKR GAILYFVLQN LNKVNSMYEY SLTSYLEVFR SSLAKTREKN NCGSSTSTDD
SKHGHDKSLQ NTITEFVNDL TLAVYEFASL GLFERDKLTL SMHMTLQILL GDGVVDIEQV
NFFTKGGFKL DGNADEDSSS NSNEAMSSTR KSFTTKALGE FWPKSGLRDL EQLVTLESSS
ERMKSLIVDI STNEDKWKKW LSSKTPEISA IPDDIQSRLT PFEFLCLLRC ARVDRITAAT
TQFISSTLGE QYVTPPIVNY DSIFNATSAR TPVVFVLSPG ADPAFDVLKL GEKKGFRLGE
KLEFMALGQG MGPRAAELIS SSAREGKWAM LQNCHLLPSW LGSLEKILED LGEVHEDFRL
WLTTEPVAAF PLGVLQSSLK VVTEPPAGLQ LNMRASFAKL SEDSLSKCNH PAFRNLSYVL
TFFHAVVQER RKYGKLGWNV PYDFNETDFR ISLSLIETYL NKVCVSDVGD EEEHDHIAAE
DPLSTISTAP KQKPKADIPW STLRYLIGEA MYGGRVSDFY DRRILVTYLN EYFGDFLFDR
DRPFAFYMCK HELSEERDDT GDKNKDTSLS VRDASPAEDD VNYQSLFGLP RQTSYEALID
AISRIPVVQT PKVLGLHMNA DVAHCTRAAK LMWENLVALQ PQITSPQAPR NANDGDDGVH
DNLTGNKAKR PEHVLDSIAV DILSVLPQKE DRNFDARKLR KKWANAITPI RIALLQELEK
HNKLTSVMKQ TLLNLRKALN GEIAMSSVLD DVAVSLNSGF VPSSWKKEAP ETGKNITSWI
QWYRKRVSQF SDWVAQHDGN LPPCVWLSGL QSPETFIAAL VQTSCRKKGW PLDVAHVKTQ
LTRVKDARSI TEPPENGCFV SGLYLEGARW DFESHALANQ KNNELVEELP VMHIIPVEKN
ESAKAGELRV PVYITQARRN AMGKGLVFEA SLQSDVHESH WVLQGVCMTL NLDD
//
