ID K8F2G6_9CHLO Unreviewed; 1080 AA.
AC K8F2G6;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=nitric-oxide synthase (NADPH) {ECO:0000256|ARBA:ARBA00012989};
DE EC=1.14.13.39 {ECO:0000256|ARBA:ARBA00012989};
GN ORFNames=Bathy09g04630 {ECO:0000313|EMBL:CCO66498.1};
OS Bathycoccus prasinos.
OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales;
OC Bathycoccaceae; Bathycoccus.
OX NCBI_TaxID=41875 {ECO:0000313|EMBL:CCO66498.1, ECO:0000313|Proteomes:UP000198341};
RN [1] {ECO:0000313|EMBL:CCO66498.1, ECO:0000313|Proteomes:UP000198341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC 1105 {ECO:0000313|EMBL:CCO66498.1,
RC ECO:0000313|Proteomes:UP000198341};
RA Genoscope - CEA;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- SIMILARITY: Belongs to the NOS family. {ECO:0000256|ARBA:ARBA00006267}.
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DR EMBL; FO082270; CCO66498.1; -; Genomic_DNA.
DR RefSeq; XP_007510938.1; XM_007510876.1.
DR AlphaFoldDB; K8F2G6; -.
DR SMR; K8F2G6; -.
DR STRING; 41875.K8F2G6; -.
DR GeneID; 19013969; -.
DR KEGG; bpg:Bathy09g04630; -.
DR eggNOG; KOG1158; Eukaryota.
DR OrthoDB; 276396at2759; -.
DR Proteomes; UP000198341; Chromosome_9.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004517; F:nitric-oxide synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006809; P:nitric oxide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.360; -; 1.
DR Gene3D; 3.90.440.10; Nitric Oxide Synthase;Heme Domain;Chain A domain 2; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR003097; CysJ-like_FAD-binding.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR008254; Flavodoxin/NO_synth.
DR InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR023173; NADPH_Cyt_P450_Rdtase_alpha.
DR InterPro; IPR044943; NOS_dom_1.
DR InterPro; IPR044940; NOS_dom_2.
DR InterPro; IPR044944; NOS_dom_3.
DR InterPro; IPR004030; NOS_N.
DR InterPro; IPR036119; NOS_N_sf.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR43410; NITRIC OXIDE SYNTHASE OXYGENASE; 1.
DR PANTHER; PTHR43410:SF1; NITRIC OXIDE SYNTHASE OXYGENASE; 1.
DR Pfam; PF00667; FAD_binding_1; 1.
DR Pfam; PF00258; Flavodoxin_1; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR Pfam; PF02898; NO_synthase; 1.
DR PRINTS; PR00371; FPNCR.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF52218; Flavoproteins; 1.
DR SUPFAM; SSF56512; Nitric oxide (NO) synthase oxygenase domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
DR PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Heme {ECO:0000256|ARBA:ARBA00022617};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000198341}.
FT DOMAIN 466..610
FT /note="Flavodoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS50902"
FT DOMAIN 659..913
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 1080 AA; 120596 MW; 0CDBD69002BEA74C CRC64;
MADEDECSNV LPVSRCPFGH GTATVDPYPG YVHGKHPAVC PRGCVPLKAD VSKAEAPKDK
LKREATEFIE LYGKENKVSE EDTMRRVAEV LESIESTGTY THTIDEIRHG ARVSWRNAPK
CINRKFYNTL DVIDAREATT NEQMFEAIKT HLKRGIGADH IPVLMTVFRP QTPGMDDGPR
IWNSQLIRYA GHRGNGEEVI GDPAELNFTD TVKKYFSWVP KSGSPGMFDC LPLVLQIDPK
QPPSIFELPE ECLLEVPIHH PNVPEISSLG LKWYGIPAVS NITLDLGGLH YTAAPFNGWY
MVTEIATRNF GDESRYNLLP KIAEAMGIDS STEETLWRDH ALAAVNFAVL YSFKRARVSI
VDHHTAAASF AQWHAEELKK RGYCPGNWKW IIPPTASSTS SIYLGLNKMT EYTLKPALVG
GMSAKSLVTR AIANGFFTPS GPGGSMMRAT LAVAKWSKRV RRVHGGVVLF ASDGGRTQSR
ATWMWSFLRQ RLPMIRPVNI ANPDVDFKTA IGECGFIMLL ASTTGSGQIP TGSQLFLDWV
NSDEGKDILK DKYFSVCAFG SKAYPKFCAG GKQFAAALRD VGASEMFNVV CIDQLDCEDV
GVQKYMRSVF DWLLSKEKMT PGVNQLLKDS LASGKAIQPP FAIKLLAHDV HGKRTEYERP
GVTATLVERE LLGSAERLST VSVTFELQDV RKGVEYYKPG DHVAVWPRTS EAQGRFFAAH
FGIEYKEFIE IVSLEDSFFS LKLAIDPAIP RRVSVADLFT KILDINAEPP AEMLASLANY
VDESECKQML EKLAREEDFR REWLEQTGVC VRTIFEQFPT LSTIHNRDKT VGVRMLQDIL
LQIPKLRARF YSVSSAPDVC GNARFALTVG RLVYRSADNA RINLGFCSDF IATLSIGTNV
TVELRPAPMF RMPKSNARPI IMLCAGTGIA PFKGFVDQLT VRSEPGAETW LIYGCRTRSN
ELYAQDMRRA EQSGHLTKYL VAYSREEGQL KTYVDAKMRQ HADDIRRLVL NEDAHVYVCG
DVRIETSVQT ALTEIMGGPE AFRALERSNK YHLDIFGAFD VQKQNENKLA NARKSLSMRE
//
