ID   K8GLN8_9CYAN            Unreviewed;       423 AA.
AC   K8GLN8;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=DUF218 domain-containing protein {ECO:0000259|Pfam:PF02698};
GN   ORFNames=OsccyDRAFT_2922 {ECO:0000313|EMBL:EKQ68391.1};
OS   Leptolyngbyaceae cyanobacterium JSC-12.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Leptolyngbyales; Leptolyngbyaceae.
OX   NCBI_TaxID=864702 {ECO:0000313|EMBL:EKQ68391.1, ECO:0000313|Proteomes:UP000001332};
RN   [1] {ECO:0000313|EMBL:EKQ68391.1, ECO:0000313|Proteomes:UP000001332}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JSC-12 {ECO:0000313|EMBL:EKQ68391.1,
RC   ECO:0000313|Proteomes:UP000001332};
RG   DOE Joint Genome Institute;
RA   Brown I., Huntemann M., Wei C.-L., Han J., Detter J.C., Han C., Tapia R.,
RA   Chen A., Kyrpides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA   Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L.,
RA   Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RT   "Improved high quality draft of Oscillatoriales sp. JSC-12.";
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKQ68391.1}.
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DR   EMBL; AJUB01000011; EKQ68391.1; -; Genomic_DNA.
DR   AlphaFoldDB; K8GLN8; -.
DR   STRING; 864702.OsccyDRAFT_2922; -.
DR   eggNOG; COG1434; Bacteria.
DR   HOGENOM; CLU_053514_1_0_3; -.
DR   OrthoDB; 526893at2; -.
DR   Proteomes; UP000001332; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd06259; YdcF-like; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR003848; DUF218.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR30336:SF4; DUF218 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR30336; INNER MEMBRANE PROTEIN, PROBABLE PERMEASE; 1.
DR   Pfam; PF02698; DUF218; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001332};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        68..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        102..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          147..370
FT                   /note="DUF218"
FT                   /evidence="ECO:0000259|Pfam:PF02698"
FT   REGION          391..423
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..423
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   423 AA;  47610 MW;  EB147D98C8E455CA CRC64;
     MVLLLTDVFL LLTQILLWIV VGLVIWYFLS KVLDRKFLGL LVLLLFLAVI ILAFFRGGID
     EPGSVLELLW RVLSFPLTPF GLGLILLFLL ITGKVAKLTR RIVIAVLILL AFSSIPLVAY
     FLAQELEMEA IELIAPVPAL EAGSRQVIVL LGRGTTRPQL RPRVNPLPPN PPPVERAITP
     DQFDVLSNLH VQITEHGDRI LYAAQLYQEE TRRGTNPLIV VSAGRRSDRR QKEGEIREDI
     TEARDIQRLL TQNLGVPENR ILLDHDNGNI RNSAERVKAL LQNQQVNFGN QIMLVASAIN
     MNRAALTFRE VFNESRIVAR PTDFFTLPQP QRLAQVATGR DLVEREIQVT DVLPTAEAFY
     ISSQALQEYL NSLYYFLRGW IKPFQAPNLN RPITSTTNQP LQTVPNQPPP ELPQPSPQSP
     TSP
//