ID   K8WH76_9GAMM            Unreviewed;       355 AA.
AC   K8WH76;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=glycerophosphodiester phosphodiesterase {ECO:0000256|ARBA:ARBA00012247};
DE            EC=3.1.4.46 {ECO:0000256|ARBA:ARBA00012247};
GN   Name=glpQ {ECO:0000313|EMBL:EKT59908.1};
GN   ORFNames=OO7_03719 {ECO:0000313|EMBL:EKT59908.1};
OS   Providencia sneebia DSM 19967.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Providencia.
OX   NCBI_TaxID=1141660 {ECO:0000313|EMBL:EKT59908.1, ECO:0000313|Proteomes:UP000010290};
RN   [1] {ECO:0000313|EMBL:EKT59908.1, ECO:0000313|Proteomes:UP000010290}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19967 {ECO:0000313|EMBL:EKT59908.1,
RC   ECO:0000313|Proteomes:UP000010290};
RX   PubMed=23145767; DOI=10.1186/1471-2164-13-612;
RA   Galac M.R., Lazzaro B.P.;
RT   "Comparative genomics of bacteria in the genus Providencia isolated from
RT   wild Drosophila melanogaster.";
RL   BMC Genomics 13:612-612(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC         glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC         ChEBI:CHEBI:83408; EC=3.1.4.46;
CC         Evidence={ECO:0000256|ARBA:ARBA00029315};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKT59908.1}.
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DR   EMBL; AKKN01000005; EKT59908.1; -; Genomic_DNA.
DR   RefSeq; WP_008914618.1; NZ_CM001773.1.
DR   AlphaFoldDB; K8WH76; -.
DR   PATRIC; fig|1141660.3.peg.753; -.
DR   HOGENOM; CLU_030226_1_0_6; -.
DR   OrthoDB; 9795622at2; -.
DR   Proteomes; UP000010290; Chromosome.
DR   GO; GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd08600; GDPD_EcGlpQ_like; 1.
DR   Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR   InterPro; IPR030395; GP_PDE_dom.
DR   InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR   PANTHER; PTHR43620:SF7; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD6; 1.
DR   PANTHER; PTHR43620; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR   Pfam; PF03009; GDPD; 1.
DR   SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR   PROSITE; PS51704; GP_PDE; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EKT59908.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010290};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..355
FT                   /note="glycerophosphodiester phosphodiesterase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003921158"
FT   DOMAIN          27..351
FT                   /note="GP-PDE"
FT                   /evidence="ECO:0000259|PROSITE:PS51704"
SQ   SEQUENCE   355 AA;  40684 MW;  C75006B1E935773E CRC64;
     MHLPLKTLVA SMILVASVSS VAQSAEKVVI AHRGASGYLP EHTLPAKAMA YAQGADFLEQ
     DLVMTKDNEL VVLHDHYLDR VTDVAERFPN RARKDGRYYA IDFTLDEIKS LNFTEGFDIV
     DGKKVQSYPN RFPMGKSDFR VHTFQEEIEF IQGLNKSTGK NIGIYPEIKA PWFHQQEGKD
     ITKKTLEVLK QYGYTNKEAN VYLQCFDANE LKRIKTKLMP EMDMNLKLVQ LIAYTDWNET
     QEQKPDGTWV NYSYDWMFEP NSMKEVAKYA DGIGPDYHML VQEDSTPDNI KLTGMVQDAH
     ANNMLVHPYT IRVDKLPKYA KDGQQLFEII YNQADVDGAF TDFPDLGVKF LQKQP
//