ID K8WVT4_9GAMM Unreviewed; 547 AA.
AC K8WVT4;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Propionate catabolism operon regulatory protein PrpR {ECO:0000313|EMBL:EKT64774.1};
GN ORFNames=OOA_01862 {ECO:0000313|EMBL:EKT64774.1};
OS Providencia burhodogranariea DSM 19968.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=1141662 {ECO:0000313|EMBL:EKT64774.1, ECO:0000313|Proteomes:UP000009336};
RN [1] {ECO:0000313|EMBL:EKT64774.1, ECO:0000313|Proteomes:UP000009336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19968 {ECO:0000313|EMBL:EKT64774.1,
RC ECO:0000313|Proteomes:UP000009336};
RX PubMed=23145767; DOI=10.1186/1471-2164-13-612;
RA Galac M.R., Lazzaro B.P.;
RT "Comparative genomics of bacteria in the genus Providencia isolated from
RT wild Drosophila melanogaster.";
RL BMC Genomics 13:612-612(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKT64774.1}.
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DR EMBL; AKKL01000005; EKT64774.1; -; Genomic_DNA.
DR AlphaFoldDB; K8WVT4; -.
DR STRING; 1141662.OOA_01862; -.
DR PATRIC; fig|1141662.3.peg.379; -.
DR eggNOG; COG3829; Bacteria.
DR HOGENOM; CLU_000445_8_5_6; -.
DR Proteomes; UP000009336; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012704; Sig_transdc_resp-reg_PrpR.
DR InterPro; IPR010524; Sig_transdc_resp-reg_PrpR_N.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR NCBIfam; TIGR02329; propionate_PrpR; 1.
DR PANTHER; PTHR32071:SF21; PROPIONATE CATABOLISM OPERON REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF06506; PrpR_N; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF159800; PrpR receptor domain-like; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 230..472
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 547 AA; 61423 MW; 4F83B11DA4935765 CRC64;
MLNETLLKSD FTNKRMGMQK PIIWTVSVSR LFTLFRDISP EFSAQADITP LNIGFEQAAE
EVRERLKIGH CDAIISAGSN GAYLKSHVSV PIIIVKVSGY DVMQALAKAR EISDKVAIIS
YQEIIPSLDE FQRNFGLQIE QRSYITAEDA RAQLKSLKAM GITVIVGAGL IMDLTHEVGM
TGIFIYSTET IRQAFYDAIE LSRISYDQKT TPIGYQSENT TKVRHTINDL IGASSVMEKV
RQYIMLYARS DATVLIQGES GTGKEMVAQA IHHEYRLFNQ HKRNKAPMPF VAVNCGAIPE
SLLEAELFGY EEGAFTGARR GGRAGLFEMA NGGTLFLDEI GEMPLALQTR LLRVLEELTI
VRIGGYRPLQ VNVRVICATH CDLDNWVKEG RFRADLFYRL GVLRMKIPSL HERGADIYML
AERLLKLAFA GLQQSLPTFR IQQLLGCSEF FEQYSWPGNV RELRNLMERV ALFCSAYADK
AITPEMLINL SPERKVKIES PATIKQAGES LAEVMSYFKG DRQAVAEYLG ISRTTLWRRL
KQDNVGG
//
