ID K8WX06_9GAMM Unreviewed; 524 AA.
AC K8WX06;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=CBS domain-containing protein {ECO:0000259|PROSITE:PS51371};
GN ORFNames=OOA_09843 {ECO:0000313|EMBL:EKT61897.1};
OS Providencia burhodogranariea DSM 19968.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Providencia.
OX NCBI_TaxID=1141662 {ECO:0000313|EMBL:EKT61897.1, ECO:0000313|Proteomes:UP000009336};
RN [1] {ECO:0000313|EMBL:EKT61897.1, ECO:0000313|Proteomes:UP000009336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19968 {ECO:0000313|EMBL:EKT61897.1,
RC ECO:0000313|Proteomes:UP000009336};
RX PubMed=23145767; DOI=10.1186/1471-2164-13-612;
RA Galac M.R., Lazzaro B.P.;
RT "Comparative genomics of bacteria in the genus Providencia isolated from
RT wild Drosophila melanogaster.";
RL BMC Genomics 13:612-612(2012).
CC -!- SIMILARITY: Belongs to the UPF0053 family.
CC {ECO:0000256|ARBA:ARBA00006337}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKT61897.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKKL01000023; EKT61897.1; -; Genomic_DNA.
DR RefSeq; WP_008911982.1; NZ_KB233222.1.
DR AlphaFoldDB; K8WX06; -.
DR STRING; 1141662.OOA_09843; -.
DR PATRIC; fig|1141662.3.peg.1999; -.
DR eggNOG; COG1253; Bacteria.
DR HOGENOM; CLU_015237_2_0_6; -.
DR OrthoDB; 9805314at2; -.
DR Proteomes; UP000009336; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR005496; Integral_membrane_TerC.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF33; UPF0053 PROTEIN YEGH; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF03471; CorC_HlyC; 1.
DR Pfam; PF03741; TerC; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Membrane {ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 304..364
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 369..425
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 524 AA; 58682 MW; DDE03927D1E31798 CRC64;
MEWIADPSIW AGLATLIVLE IVLGIDNLVF IAILADKLPQ KMRDRARITG LMLALIMRIV
LLFSLSWLIT LTKPLVTLFD HPFSARDLIM LIGGIFLLFK ATMELNERLE GGDEHTNTQR
KTSNFWAVVA QIIVLDAVFS LDSVITAVGM VDHIGVMVAA VTIAMILMIW ASKPLTGFVN
NHPTIVILCL SFLLMIGFSL VAEGFGYPIP KGYLYAAIGF SIMIEVLNQF AQFNRRKYLK
GARPLRERTA EAVLRILSGK HERAELDAHT SNLIADNQSV FDPQERRMIA RVLGMAQRNV
ESIMTSRHDV DYLDINKSAS DLLQLMEKNP HSRFVVIDET VSDEPVGVVH ILDLVKQQLS
GAPLDLRALI TQPLIFPEGL SLLKALEQFR KAHTHFAFVV DEFGSIEGIV TLTDVMETIA
GNLPVGEEEN DSRHDIQKLE DGSWVANGFM PLEDLILFIP MELDDKREYE TIAGLLMEDL
QRVPQVGEQV EVNGCIFQPL EINSHRISKV LIIPPKTSHE YEEA
//
