ID K8YFA4_9LEPT Unreviewed; 786 AA.
AC K8YFA4;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Ammonium transporter {ECO:0000256|RuleBase:RU362002};
GN ORFNames=LSS_03584 {ECO:0000313|EMBL:EKT88035.1};
OS Leptospira santarosai serovar Shermani str. LT 821.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=758847 {ECO:0000313|EMBL:EKT88035.1, ECO:0000313|Proteomes:UP000035800};
RN [1] {ECO:0000313|EMBL:EKT88035.1, ECO:0000313|Proteomes:UP000035800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT 821 {ECO:0000313|EMBL:EKT88035.1};
RX PubMed=23041083; DOI=10.1016/j.gene.2012.09.074;
RA Chou L.F., Chen Y.T., Lu C.W., Ko Y.C., Tang C.Y., Pan M.J., Tian Y.C.,
RA Chiu C.H., Hung C.C., Yang C.W.;
RT "Sequence of Leptospira santarosai serovar Shermani genome and prediction
RT of virulence-associated genes.";
RL Gene 511:364-370(2012).
RN [2] {ECO:0000313|Proteomes:UP000035800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT821 {ECO:0000313|Proteomes:UP000035800};
RA Chou L.-F., Chen T.-W., Ko Y.-C., Pan M.-J., Tian Y.-C., Chiu C.-H.,
RA Tang P., Hung C.-C., Yang C.-W.;
RT "Potential impact on kidney infection: a whole-genome analysis of
RT Leptospira santarosai serovar Shermani.";
RL Emerg. Microbes Infect. 3:e82-e82(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362002};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362002}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ammonia transporter channel (TC 1.A.11.2)
CC family. {ECO:0000256|ARBA:ARBA00005887, ECO:0000256|RuleBase:RU362002}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP006694; EKT88035.1; -; Genomic_DNA.
DR RefSeq; WP_004458448.1; NZ_CP006694.1.
DR AlphaFoldDB; K8YFA4; -.
DR STRING; 758847.LSS_03584; -.
DR GeneID; 29741829; -.
DR KEGG; lst:LSS_03584; -.
DR PATRIC; fig|758847.3.peg.746; -.
DR Proteomes; UP000035800; Chromosome I.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR001905; Ammonium_transpt.
DR InterPro; IPR018047; Ammonium_transpt_CS.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR NCBIfam; TIGR00836; amt; 1.
DR PANTHER; PTHR11730; AMMONIUM TRANSPORTER; 1.
DR PANTHER; PTHR11730:SF89; AMMONIUM TRANSPORTER SLL0108-RELATED; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS01219; AMMONIUM_TRANSP; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
PE 3: Inferred from homology;
KW Ammonia transport {ECO:0000256|ARBA:ARBA00023177,
KW ECO:0000256|RuleBase:RU362002};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362002};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362002};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362002};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362002}.
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 121..143
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 150..172
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 184..205
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 226..243
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 255..281
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 311..330
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 342..360
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT TRANSMEM 372..393
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362002"
FT DOMAIN 474..728
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 786 AA; 85760 MW; 9010C27FD817192F CRC64;
MKNLKRHRMI NRIALILFLG INPPLFSESP ALELSKTVDP IWLILCAALV FFMQAGFLML
ETGLSRLKNT INVAVKNLMD YIVGTIAFFC VGFALMFGFS YEGWIGTNHF FLSGLKTGKD
FSFFLFQVAF MGTAATVVSG AVAERIKFSA YLVVSIVVSI FIYPIFGHWT WGGGWIAKTG
FVDFAGSTVV HSLGGWVALA GVIVLGPRKD KFKEDGTPKK IHGHNLTFSV LGVFILWFGW
FGFNGGSTLS FTDEVPLIIL NTSLSGSAGG ILAITLSWIF YRVASVEDCM NGVLGGLVAV
TAGCHAIQPH AALLIGSVAG VSVVITSWVL EKILKLDDVV GAFPVHGVCG ILGTLLLPAL
SENQDIRIFP QLIGVAICSF WAFGLGLILF LLLKISIGIR VKEEFEEQGL NVAEHGAGSS
WIDLIHSLKD LAKGGGDLTR KIHVDSGTEA GAIAFLMNRY LANLGQMIYT IKEKSGELEN
SAFEISTAWG KMSHGIQEQA ANLEEVTSIF DSFRESFQRI SSSVTQQKEI ETNAKQLLSE
LVVGFQKFDS DLKNSSEKSE KSVQTIESSR KELNHLESDI NDIGSSAKKV ENIVKLLNDI
SAKLGILSIN ASIEAARSGD AGKGFGVVAE EINKLASNTQ ESTKKASEIL GEIQSTVSRG
KNTVLTTVEF FKNLTEEFRF LAMTQITIRQ NSSHYSQLIE NLNRLNTSIT NQSEIITTDI
EGRFSEIGNL YESVDLINEA FHEISAQSEE LTATGDFLKQ LAGILNSLVR NFRVEQNVSQ
EWITGS
//
