ID K8YQT3_NANGC Unreviewed; 1048 AA.
AC K8YQT3;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Two-pore calcium channel {ECO:0000313|EMBL:EKU20934.1};
GN ORFNames=NGA_0121300 {ECO:0000313|EMBL:EKU20934.1};
OS Nannochloropsis gaditana (strain CCMP526) (Green microalga)
OS (Microchloropsis gaditana).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX NCBI_TaxID=1093141 {ECO:0000313|EMBL:EKU20934.1, ECO:0000313|Proteomes:UP000009377};
RN [1] {ECO:0000313|Proteomes:UP000009377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP526 {ECO:0000313|Proteomes:UP000009377};
RX PubMed=22353717;
RA Radakovits R., Jinkerson R.E., Fuerstenberg S.I., Tae H., Settlage R.E.,
RA Boore J.L., Posewitz M.C.;
RT "Draft genome sequence and genetic transformation of the oleaginous alga
RT Nannochloropis gaditana.";
RL Nat. Commun. 3:686-686(2012).
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DR EMBL; JH470777; EKU20934.1; -; Genomic_DNA.
DR RefSeq; XP_005855427.1; XM_005855365.1.
DR AlphaFoldDB; K8YQT3; -.
DR EnsemblProtists; EKU20934; EKU20934; NGA_0121300.
DR GeneID; 17362200; -.
DR KEGG; ngd:NGA_0121300; -.
DR OMA; LLICRIM; -.
DR OrthoDB; 5403296at2759; -.
DR Proteomes; UP000009377; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR InterPro; IPR005821; Ion_trans_dom.
DR PANTHER; PTHR46726; TWO PORE CHANNEL 3; 1.
DR PANTHER; PTHR46726:SF1; TWO PORE CHANNEL 3; 1.
DR Pfam; PF00520; Ion_trans; 2.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009377};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 162..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..518
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..584
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 596..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 634..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 676..698
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 718..740
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 167..390
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 497..738
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 751..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..1003
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 751..776
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..953
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 954..976
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 987..1003
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 118934 MW; 76FB52BF31FFF5FB CRC64;
MMENEGDPGK GLDVSRTSDY GAIPTFHDAA LTHPEESENV STPTSQAFNT LPSSVHASDS
ELDHVYATVE SGNALAIKDF PVLQTTSAAI LPRWIYRYFP CLRFLPTWSC FPDPTQGPLL
SPRRNLEFFR AILYLLDGGR KQQSHFQDDA KSMRFYYLRQ TLAYRTCIIV ACIMYLSISL
TEAPNFQIYS RKREQVSRDT SHGYELTFNV ISVLFFVLDI WIQFQAMGKK KTFGYRWTQL
FVVLLAFDVV GMAWPQARLL MVTGIVRCYP IVYYSKKARN AMLDYLRTVP SVIQWIGIEF
LSVLVFACFA VILYASVDRG GASEQTAFLS LNRAFISLYE LSLTVNDPDI YLPYYRIDAL
NAILFVAFLI LTFFLLHNII LASVFRIYSA KLRDTAVRRN SYRESALNLA FRALVGENQG
PTGRVHKDLL AHVLKRVFPH HSSEKISAFM QYADREDSND DDQDYDYDRF LILMSAIADD
CLHVIRPSVA YPGRLHSFLD VLVLAELLVA VVAVARYWHI FYKIWLVATL AAFRFIFALD
IIYGLLQIKG FKIYLKSSVH KCKLFALLFF LVALVCMLTN DRVLGESKEV NMTQKAASMF
LLLSVFADVV RLSTRVPEYA ALVQVFRDLL VPALLSQATV IFFLMHLTCY AGMYLFGGRI
YPSQPIWATL PFPGSLYYLL NFNTYREGML TLFMLLVVNN WNQISAQFVR VTHPAAYLFF
MAYQVLVVTI ALSCVTSFFI THLSNQLGEE LEKGRKRKEG KEDKVEGKEN QKKKKEGTFS
WGGWGSWLSA DNRKGSMDEL QEREDETYAL RFVPKSGIIL GTRSPSLSEQ FFSLRGLEPV
PDLASGTLPS EKAALRDEQP VADVEYQCLL EALLKEKGQE FAYCFIKEQR NKSHLESFNR
STGFARIIRP YPQAESSLLK TCADLFGKDM SKQGKKEGGN SSDLSTPSSE GRRKTEGGNG
DEITGKAEEK SETKQIKGAA EGAAAGEEEE IMVEDEEEDA DDMGEKRDCV MIQDIMPHPS
ESCRALYMKI YFMYGGDNKL AFCQLHEQ
//
