ID K8Z7Q8_NANGC Unreviewed; 2104 AA.
AC K8Z7Q8;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Translation initiation factor if-2 {ECO:0000313|EMBL:EKU21776.1};
GN ORFNames=NGA_0236400 {ECO:0000313|EMBL:EKU21776.1};
OS Nannochloropsis gaditana (strain CCMP526) (Green microalga)
OS (Microchloropsis gaditana).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Eustigmatophyceae;
OC Eustigmatales; Monodopsidaceae; Nannochloropsis.
OX NCBI_TaxID=1093141 {ECO:0000313|EMBL:EKU21776.1, ECO:0000313|Proteomes:UP000009377};
RN [1] {ECO:0000313|Proteomes:UP000009377}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP526 {ECO:0000313|Proteomes:UP000009377};
RX PubMed=22353717;
RA Radakovits R., Jinkerson R.E., Fuerstenberg S.I., Tae H., Settlage R.E.,
RA Boore J.L., Posewitz M.C.;
RT "Draft genome sequence and genetic transformation of the oleaginous alga
RT Nannochloropis gaditana.";
RL Nat. Commun. 3:686-686(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
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DR EMBL; JH471035; EKU21776.1; -; Genomic_DNA.
DR RefSeq; XP_005854583.1; XM_005854521.1.
DR EnsemblProtists; EKU21776; EKU21776; NGA_0236400.
DR GeneID; 17361356; -.
DR KEGG; ngd:NGA_0236400; -.
DR OMA; VHECIRI; -.
DR OrthoDB; 169393at2759; -.
DR Proteomes; UP000009377; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01887; IF2_eIF5B; 1.
DR CDD; cd03692; mtIF2_IVc; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF20; TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF11987; IF-2; 1.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 2.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540,
KW ECO:0000313|EMBL:EKU21776.1};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000009377}.
FT DOMAIN 474..680
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 74..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1083..1121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1141..1160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1175..1423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1470..1556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1571..1619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1730..1776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1799..1843
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1947..1974
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 80..113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1190..1205
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1206..1220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1293..1307
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1382..1396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1399..1415
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1805..1843
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2104 AA; 227802 MW; 6DFC733FBBD6FDA1 CRC64;
MENPIDAAQL FKYSPTARAT PRVGHSGRRK GQKSRDEAAL SAIGLGESVH ALPETLLEGS
SLAHQAVNPL ARLKPNGRAA NSVNAASGNK LKVNAKDKTQ QPSQQTTPLR GARKQEGSSG
GGRPKVKGAA AFLQQQRLGG QKAQSMLGND TMNGVNGSAK DRFSNRVLPS ESSSQPGNQL
PSGRAALASG GRHGSIPPGK SGGNSMDMAT YQRFSDLGQR LANARTNLEQ SQQRPGRRQQ
AWQPSSKPRL QASSAPSWPP PSNHEHPQYR QEGFAGFALA NGESVEKGKV SGNRLDRGRW
GAPATAAAAP AAVSPIGAEH VRLWEVDLGE RKSASSRAPV LSREESHENQ KIRSQELQQR
QRRRQGRKGP RLGRRLRALQ RVPLVLPHEP IAVRELAQKL SLKMKDVGER VLRLGGSEEY
YNWNPETKVD LDVAELVGLE LGRTVKRMAP PENLLEYRSR VREGRGGRRV EWPLRPPVVC
VMGHVDHGKT TLLDALRQSR VAAAEAGGIT QRLGAFHIPG VGEGGEEGGL GITVLDTPGH
AAFRAMRMHG ALATDIVLLV VSATDGLQEQ TLEVLRMLEE QWAEEEEDFC MQRGGEGGKM
EGFSPSLSLM VAVTKVDKLH GEEEVQTALS KIEHALAAHG IMSEALGGDV QVVPVSAVTG
AGLPDLLDRV RLQAEMLELR ADREGPGEGV ILDAGMEKGL GMVMSVLMRW GSLAPGDVVV
AGEQWGRVKK ILGARNSPGG PVDRALPSMP VRVLGLRDLP TPGQEVIVVK SEERAEAVAK
ARREAAERRR YQETAATEVL GEEEQEQLQE ILDKNLVGAN VGGKKTKAYL ALQRGAVDDL
LDSASAKREG GQEGPVVVPF LVKADGKGTL DAVTAALAAY EHDTIRTEVI GTGCGPVTEG
DVEKAKGVAA RECDGGGEAC TILAFNVGFV NAEVGEMARR EGVRVKKEDV IYTLLEQTKA
TLQEHMPWER VETSVGKMEV QAVFTLTGKR RARNTVAGCK VVSGGVFSGQ QYRYRVMRGG
EVVCKESPPA TLYHFKEQVQ EVKKGQECGL ALEGFGAFEA GDVIECYTVT EKQRSIAETA
FGRGARPSAS PPLCTHFPKS GPFPSLKPGG GRSRRGGRER APARCLRPAY RCEATPPRPT
LSHIPCGPSR VRRRRRQRPG RGLARLWDPF IRRSLPAPPF LPPTLPRSFL PSWSVGSSPS
LPTLHSRREG RQREARARDQ GSLPGHGLRR FQEQRHPTAL PRPQCPGEAL GRGHSAAHRG
ENGASSGGGG GGGGGXXXAR GEKAHEAVVE GEREEEVGEE VLNEEGEEEE PRPFTSFRPS
FASFLLNHQM LRPPPHVVPP SHNQDLPRHP APAVSTARGK KTPPLKQPKR KAKPDRDPNG
QGRRATSLTG VSEGNDQAYK SPRHVRREKQ EEGKSQRPLS PAPSTQVVIV SELRILWTLA
ARQAVNHFST QVTRHMHQYN TIQITPSIME RKCAEVPGRE GRTSSSSTES SEGEDEEEEE
LPGSLSWSQS RSERISPFYS PPPRDTRTPP PGQSDLARMF LHPSRDGALP APELSEHDVL
SQSVRPRSSF VLGGMGGGLE MQAGGPRAGA PEAGDESRPS IPPGASPDTE GGRGGRGTRS
KLDYRVTFKV VLLYPQLNFR SQHANGSFII AAQEAYMEGR QHEKLFRRRC EPLSGLTPAL
GPARPPVKLL AKVEQWLRIE NMRAYVVPLD VEVTREVHWL EVVPASDEPV LGEEEKPGAS
TKLTAMMGMV EAGGGGGPGG KRERESSRSA SPSASLRSLS PLAAAMGIGR VGFGKAFGGK
GGKKGASSET SSPGHRSDAQ STHVGNRKSN STSGRRKQSS ARPEYAFQGS AVVQEVVKDF
GLTFASIAFK PAALPKAGSR EVSAFSQSLE ESGGSRCNSN GEKVRRIRIS SEETVAKVLL
DLPQLDWNLN SRQFYITLDV IRNVLLAAPV QTEEEEAEER IRREQQEAKR IAEARQRVAA
VAGLNPGEEK GGLELALEPE HLDLGSKSDR DVLKTLVEQT LQRLLLPTLH ETKMVQYCVG
GGTWKVKAEE GMLTKYDALE IGFTGFSGQH VYFHDGSMDS TVQVESFWPR RPGQATLPTL
WRPL
//
