ID K9AS38_9MICO Unreviewed; 493 AA.
AC K9AS38;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:EKU48841.1};
GN ORFNames=C272_04760 {ECO:0000313|EMBL:EKU48841.1};
OS Brevibacterium casei S18.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC Brevibacterium.
OX NCBI_TaxID=1229781 {ECO:0000313|EMBL:EKU48841.1, ECO:0000313|Proteomes:UP000009879};
RN [1] {ECO:0000313|EMBL:EKU48841.1, ECO:0000313|Proteomes:UP000009879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S18 {ECO:0000313|EMBL:EKU48841.1,
RC ECO:0000313|Proteomes:UP000009879};
RA Sharma R., Singh A., Jangir P.K.;
RT "Genome Sequence of Brevibacterium casei S18.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKU48841.1}.
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DR EMBL; AMSP01000002; EKU48841.1; -; Genomic_DNA.
DR AlphaFoldDB; K9AS38; -.
DR PATRIC; fig|1229781.4.peg.956; -.
DR eggNOG; COG1012; Bacteria.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000009879; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07097; ALDH_KGSADH-YcbD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000009879}.
FT DOMAIN 35..487
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 262
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 493 AA; 51668 MW; 8E01D9EF9700906A CRC64;
MTQPQQSAAT ADSGEDNLVD NLIGGKRRGS DDRTLNRNPS DPADVIGSFA RADEQAVRDA
IAAANAAAPE WADFPAQQRF GILDRAGSLI AERADELADL LAREEGKQLG ESRGEVLRAS
QIFKFFAGET IRNTGEIIDS VRPGLTAEMT HEPIGVVGII TPWNFPIAIP AWKIAPALAY
GNTVVFKPAE LVPGSAAALV DILVEAGLPD GVINLVMGPG RVVGEVLTTS ADVDAITFTG
SVAVGRGVIA AASEHGIRVQ AEMGGKNPLV VLGDADLEAA ADAAINGAFF STGQRCTASS
RLIVTDDVHD EFVALLKERM AALTVGDARA EGTDIGPVVS ETQLEQDLRY IGIARDEGGE
VTGGDRVEAA TDGYFLAPAL VTGTKPADTI NVEEVFGPVA SVIRVADYDE ALAVANDTAF
GLSAGIYTTS LKYSTHFKRY AQAGMVMVNA PTAGVDYHVS FGGRKGSSYG PREQARAARE
FYTVQKTAYV NAG
//
