GenomeNet

Database: UniProt
Entry: K9B0Y0_9MICO
LinkDB: K9B0Y0_9MICO
Original site: K9B0Y0_9MICO 
ID   K9B0Y0_9MICO            Unreviewed;       537 AA.
AC   K9B0Y0;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   25-OCT-2017, entry version 37.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=C272_06119 {ECO:0000313|EMBL:EKU48462.1};
OS   Brevibacterium casei S18.
OC   Bacteria; Actinobacteria; Micrococcales; Brevibacteriaceae;
OC   Brevibacterium.
OX   NCBI_TaxID=1229781 {ECO:0000313|EMBL:EKU48462.1, ECO:0000313|Proteomes:UP000009879};
RN   [1] {ECO:0000313|EMBL:EKU48462.1, ECO:0000313|Proteomes:UP000009879}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S18 {ECO:0000313|EMBL:EKU48462.1,
RC   ECO:0000313|Proteomes:UP000009879};
RA   Sharma R., Singh A., Jangir P.K.;
RT   "Genome Sequence of Brevibacterium casei S18.";
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EKU48462.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AMSP01000003; EKU48462.1; -; Genomic_DNA.
DR   EnsemblBacteria; EKU48462; EKU48462; C272_06119.
DR   PATRIC; fig|1229781.4.peg.1228; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000009879; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000009879};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009879}.
FT   DOMAIN      224    357       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      441    510       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     232    239       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   537 AA;  59200 MW;  C900F228CE11AC6E CRC64;
     MSNSKNELIG QWQTVVSTLD QDADLTRHQK SFLYLALPKA LVDNALVLLA VRDEHSRRTI
     ETRLLEPLTR EFSKVIGFDV TFGFVVDPEL DVPIRFDELI DDASAEPSTA AETTAPTASD
     AAPAPAPAPA TEIDEPAVAP PAAPEPSPVG NSAPAPSADT GTRPADSRIE VEIAEATTTP
     TPPVDVPGVA QLNPKYTFDT FVIGASNRFA HAAAFAVAEA PAKAYNPLFI YGDSGLGKTH
     LLHAIGFYAT QLFPEIRVKY VSSEEFVNDF INTIGSSRTS NALRPAFQRR YREVDILMID
     DIQFLQGKDA TVEEFFHTFN ALHNEAKQVV ITSDQPPKML KGFEERLRSR FEWGLLTDVQ
     PPDMETRFAI LRRKAAGEHL DVPDDVLEYI ASRVSSNIRE LEGALIRVTA FANLNDQQVD
     VSLAETVLKD FITQDDTPAI TAADIMGQTA AYFSLTLDDL CGTSRSRTLT TARQIAMYLC
     RELTDLSLPK IGQAFGGRDH TTVMHANKKI RTQMAERRAV YTQVTELTNR IKQQHRL
//
DBGET integrated database retrieval system