ID   K9D501_SPHYA            Unreviewed;       327 AA.
AC   K9D501;
DT   06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Thioredoxin reductase {ECO:0000256|ARBA:ARBA00018719};
GN   ORFNames=HMPREF9718_04827 {ECO:0000313|EMBL:EKU72660.1};
OS   Sphingobium yanoikuyae ATCC 51230.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=883163 {ECO:0000313|EMBL:EKU72660.1, ECO:0000313|Proteomes:UP000009887};
RN   [1] {ECO:0000313|EMBL:EKU72660.1, ECO:0000313|Proteomes:UP000009887}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51230 {ECO:0000313|EMBL:EKU72660.1,
RC   ECO:0000313|Proteomes:UP000009887};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Huys G., Walker B., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Sphingobium yanoikuyae ATCC 51230.";
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|ARBA:ARBA00001974};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKU72660.1}.
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DR   EMBL; AGZU01000019; EKU72660.1; -; Genomic_DNA.
DR   AlphaFoldDB; K9D501; -.
DR   PATRIC; fig|883163.3.peg.4869; -.
DR   HOGENOM; CLU_031864_5_0_5; -.
DR   Proteomes; UP000009887; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   PANTHER; PTHR48105; THIOREDOXIN REDUCTASE 1-RELATED-RELATED; 1.
DR   PANTHER; PTHR48105:SF28; THIOREDOXIN REDUCTASE GLIT (AFU_ORTHOLOGUE AFUA_6G09740); 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00469; PNDRDTASEII.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009887}.
FT   DOMAIN          15..293
FT                   /note="FAD/NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF07992"
SQ   SEQUENCE   327 AA;  34268 MW;  9DA99E9348F34A69 CRC64;
     MTDQGWTGDP EEVIDCLIVG GGPAGLMTAI YLSRFLRSCV VYDAAAGRAA SIPRSHNLPG
     FPGGISGVAF LARLQAQLRE YGGTIQRGEI DAIVASGDHF SASCELNVLY ARTVVLATGV
     VNRRPEMPDA MHDIGVARGL LRYCPICDGY EARRMNVAVL GGSGHGAEEA EFLRAYGAKV
     TLLAEHSLDL GPTELAKLDQ QGIDVAPSPV EQLRLGDCVE VRLANGLELQ FDTLYPALGS
     SPRTRLASLL GAQLSESGCV LTNAHQQTSV KGLYAVGDAV EGLDQISVAA GQAAIAATAI
     HNMLRDRDSG LSSAIAGLYP ARSVPPT
//