ID K9EK50_9BACE Unreviewed; 773 AA.
AC K9EK50;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=HMPREF9447_02953 {ECO:0000313|EMBL:EKU89515.1};
OS Bacteroides oleiciplenus YIT 12058.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=742727 {ECO:0000313|EMBL:EKU89515.1, ECO:0000313|Proteomes:UP000009872};
RN [1] {ECO:0000313|EMBL:EKU89515.1, ECO:0000313|Proteomes:UP000009872}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 12058 {ECO:0000313|EMBL:EKU89515.1,
RC ECO:0000313|Proteomes:UP000009872};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Morotomi M., Walker B.,
RA Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides oleiciplenus YIT 12058.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKU89515.1}.
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DR EMBL; ADLF01000013; EKU89515.1; -; Genomic_DNA.
DR RefSeq; WP_009130491.1; NZ_JH992942.1.
DR AlphaFoldDB; K9EK50; -.
DR STRING; 742727.HMPREF9447_02953; -.
DR PATRIC; fig|742727.4.peg.3021; -.
DR eggNOG; COG3525; Bacteria.
DR HOGENOM; CLU_007082_5_0_10; -.
DR OrthoDB; 1090159at2; -.
DR Proteomes; UP000009872; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR026876; Fn3_assoc_repeat.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF13287; Fn3_assoc; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 28..158
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 161..508
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 339
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 773 AA; 87801 MW; 06AEC25E2CD3761D CRC64;
MKIAYWILAA SFTLLSCGEG HNDGMKDYGI IPMPNGIVPE QGKYILQGEK TVAVSSEELS
MKVFQYFENA LKNTSVTLKR VSLTEQADIS FLINDTLPDE AYTLEVSSHN IKISSNASAA
GLFYGVQSLL QLMPSEIYDT QQKYESNIEI PAVNITDAPR FPYRGAMMDV GRNFLPKEEV
LKFLDLMAMY KLNKFHFHLT DDQGWRIEIK KYPKLTEIGS HRKQTQVGHC DYYYPRRFDG
KEKEGYYTQD EIREIVKYAS DRFITVIPEI EMPGHASAAL ASYPELSCGL GKTYVVRDYF
DVFDEVYCPK EGTFDFLEGV LTEVIDLFPS HYIHIGGDEC PKKAWKKCDH CQALMKREGL
KDEESLQSWF IHRIEQFVNS KGRDIIGWDE ILEGGLAPNA TVMSWRGEEG GIEAARQKHK
VIMTPGDKCY IDHYQESPEF APLAIGGFLP LDSVYTYNPL PVELTPEEQA YIIGTQANVW
GEYIQTPEYF EYMAFPRLLA MSEVQWTQPE NKNLSSFVRR LDGEFKRLDY CGVNACRNFY
EVNLTGAWND SRHVYEVTLK TFCPDTEIYY TINDSVVSSS SNLYKAPVSL SEDATVYAAV
YRDGKPLGRI THKGFAMNKA TGNPYECVPP PVAEKVNEGI GLTDGIPGYT RDLRRWVIFR
GDTVRITVDL GKAVPVNRVA FAFLWRPFDT LWPASKLSVS VSTDSKTFTS VGSKEYSYDF
TPTEATRFPV SYSFPEVTAR YICLELLNGG LCPEGYYHAG QQSRLAIDEI EFY
//
