ID K9F8T4_PEND2 Unreviewed; 692 AA.
AC K9F8T4;
DT 06-FEB-2013, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Acetoacetyl-coa synthetase, putative {ECO:0000313|EMBL:EKV05825.1};
GN ORFNames=PDIG_80220 {ECO:0000313|EMBL:EKV05825.1};
OS Penicillium digitatum (strain PHI26 / CECT 20796) (Green mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=1170229 {ECO:0000313|EMBL:EKV05825.1, ECO:0000313|Proteomes:UP000009882};
RN [1] {ECO:0000313|Proteomes:UP000009882}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHI26 / CECT 20796 {ECO:0000313|Proteomes:UP000009882};
RX PubMed=23171342; DOI=10.1186/1471-2164-13-646;
RA Marcet-Houben M., Ballester A.-R., de la Fuente B., Harries E.,
RA Marcos J.F., Gonzalez-Candelas L., Gabaldon T.;
RT "Genome sequence of the necrotrophic fungus Penicillium digitatum, the main
RT postharvest pathogen of citrus.";
RL BMC Genomics 13:646-646(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKV05825.1}.
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DR EMBL; AKCT01000296; EKV05825.1; -; Genomic_DNA.
DR AlphaFoldDB; K9F8T4; -.
DR STRING; 1170229.K9F8T4; -.
DR eggNOG; KOG1175; Eukaryota.
DR HOGENOM; CLU_000022_3_3_1; -.
DR InParanoid; K9F8T4; -.
DR OMA; MPNTWQT; -.
DR OrthoDB; 45466at2759; -.
DR Proteomes; UP000009882; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd05943; AACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000009882}.
FT DOMAIN 43..100
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 111..499
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
SQ SEQUENCE 692 AA; 76703 MW; 578DE45E309A1D10 CRC64;
MPHIEIVEPE VKELWRSSSP EATQVYDFMT KVNKKYGLTL NDYNALWKWS VSEPAQFWEE
IWHYTKIHAH KPYQQILDSK DVLFPRPSFF EGSTLNFAEN LLYPARAPDE DSVAVIGATE
AAREFISWKE LRERVRLCAN ALKEAGLKTG DRVAGFVGNH ANTVVAMLAA ASIGAFWTGV
SPDTGVHAVL ERLKQIQPKI LFADNGSFYN GKVHSSQVKV REIVSELPDL ELLVLLITTP
ELEVNLDDLR PANGKAKVYD DFVSEVKNPQ VPLEFASLRP DHPVYILYSS GTTGAPKPIV
HGSLGTLLQH KKEHLLHCDI RPGDRLFYFT TTTWMMWHWL VSGLASGATI VLYDGSPFRP
FDDEGGKGEM AMPRLIEELQ ITHFGTSAKY LSLLEQAALN PRKHAHRPVS LKTLRAIFST
GSPLAPSTFE YVYSSFHHDI MLGSITGGTD ILSLFASGCP ILPVHRGEIQ CRSLGMDISV
FDYAGNDISA TGEPGDLVCI TPFPAQPVMF WPPGSIGSEK YRKSYFDVFG PSVWHHGDYV
RFNPQTGGVV MLGRSDGVLK PSGVRFGSAE IYNILLKHFA DDVEDSLCIG RRREGIDTDE
TVVLFIRLTS GNESGMPADL AARIQSTIRK ELSPRHVPGI IDACPEIPVT SNGKKVENAV
KQILCGLNIK IGASVANASC LDWYRTWASE HP
//
